HitPredict

Interactor 1: MYL6 (P60660)
Myosin light polypeptide 6 (17 kDa myosin light chain) (LC17) (Myosin light chain 3) (MLC-3) (Myosin light chain alkali 3) (Myosin light chain A3) (Smooth muscle and nonmuscle myosin light chain alkali 6)
Gene: MYL6

Interactor 2: IKKE (Q14164)
Inhibitor of nuclear factor kappa-B kinase subunit epsilon (I-kappa-B kinase epsilon) (IKK-E) (IKK-epsilon) (IkBKE) (EC 2.7.11.10) (Inducible I kappa-B kinase) (IKK-i)
Gene: IKBKE

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	17353931, 14743216
Identification Methods	anti bait coimmunoprecipitation, tandem affinity purification
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 151 Hs			1 716
+	Hs
		167507 MYL6_HUMAN (1-151): 9.61e-42: 137: 100.00		IKKA_HUMAN (9-700): 5.05e-116: 367: 18.31
+	At
		187626 CDPKF_ARATH (73-150): 3.57e-11: 61.7: 26.58		CIPKD_ARATH (6-485): 8.66e-121: 372: 19.55
+	At
		989461 CDPK1_ARATH (73-150): 1e-09: 57.5: 21.52		KIN10_ARATH (9-469): 1.39e-121: 374: 17.42
+	Hs
		483929 CALM1_HUMAN (5-77): 1.13e-11: 60.6: 28.77		KCC1A_HUMAN (3-389): 7.57e-121: 367: 20.16
+	At
		1105900 CDPKB_ARATH (73-150): 4.48e-09: 55.6: 22.79		CDPKB_ARATH (3-372): 1.93e-120: 371: 16.45
+	Hs
		648500 CALL3_HUMAN (5-77): 1.25e-10: 57.9: 26.03		KCC1A_HUMAN (3-389): 7.57e-121: 367: 20.16
+	Ce
		183804 CALM_CAEEL (5-77): 2.09e-11: 59.8: 30.14		CMK1_CAEEL (13-221): 5.69e-22: 99.8: 33.65