Protein: GSK3
Glycogen synthase kinase-3 (EC 2.7.11.26)

Gene: GSK3, gsk-3
Organism: Caenorhabditis elegans
Interactions: 24
UniProt ID: Q9U2Q9

Gene Ontology (top 5):
GO:0000132 - establishment of mitotic spindle orientation
GO:0004674 - protein serine/threonine kinase activity
GO:0005524 - ATP binding
GO:0005634 - nucleus
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

264040

PRY1
Axin-like protein pry-1

4

0

Small-scale

0.861

High

1445261

MAC1
Protein mac-1

3

6

High-throughput

0.661

High

814472

MPK1
Mitogen-activated protein kinase mpk-1

1

14

Small-scale

0.647

High

759089

PLK1
Serine/threonine-protein kinase plk-1

1

8

High-throughput

0.618

High

1355777

MBK1
Dual specificity tyrosine-phosphorylation-regulated kinase mbk-1

1

19

High-throughput

0.618

High

1457935

MBK2
Dual specificity tyrosine-phosphorylation-regulated kinase mbk-2

1

19

High-throughput

0.618

High

760191

SKN1
Protein skinhead-1

2

0

Small-scale

0.603

High

1171107

TPM1
Tropomyosin isoforms a/b/d/f

2

5

High-throughput

0.576

High

1165184

AKT1
Serine/threonine-protein kinase akt-1

1

20

Small-scale

0.575

High

111053

G5ECP6
C2H2-type domain-containing protein

2

1

High-throughput

0.542

High

110644

G5EC71
glutathione transferase

1

4

High-throughput

0.541

High

233777

O45233
Alcohol dehydrogenase transcription factor myb/sant-like protein

1

2

High-throughput

0.541

High

1171021

Q22757
GSKIP domain-containing protein

1

3

High-throughput

0.541

High

233246

O44490
ELKS/RAB6-interacting/CAST family member 2

2

18

High-throughput

0.533

High

110690

MOE1
CCCH-type zinc finger protein oma-1

1

4

Small-scale

0.501

High

1171309

MOE2
CCCH-type zinc finger protein oma-2

1

6

Small-scale

0.501

High

1170880

Q22436
ZZ-type domain-containing protein

1

6

High-throughput

0.494

High

98552

F1LIM5
ZZ-type domain-containing protein

1

6

High-throughput

0.481

High

1457571

Q9TXM1
Uncharacterized protein

1

0

High-throughput

0.458

High

1166954

Q19902
C2H2-type domain-containing protein

1

1

High-throughput

0.451

High

1186993

AXLP1
Axin-like protein 1

2

0

Small-scale

0.339

High

233481

O44761
Ribosome biogenesis protein NOP53

2

0

High-throughput

0.300

High

1165086

Q17798
Histone deacetylase HDT1

1

0

High-throughput

0.292

High

96524

E9P875
Neurexin-3-beta

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025