HitPredict - High confidence protein-protein interactions

Interactor 1: ACTB (P60709)
Actin, cytoplasmic 1 (EC 3.6.4.-) (Beta-actin) [Cleaved into: Actin, cytoplasmic 1, N-terminally processed]
Gene: ACTB

Interactor 2: SMCE1 (Q969G3)
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1 (BRG1-associated factor 57) (BAF57)
Gene: SMARCE1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.71	0.60	0.656

Property	Details
Experiments	35271311, 9845365, 18809673
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000776 - kinetochore GO:0000785 - chromatin GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006338 - chromatin remodeling and 18 others more... GO:0006357 - regulation of transcription by RNA polymerase II GO:0016363 - nuclear matrix GO:0016514 - SWI/SNF complex GO:0016586 - RSC-type complex GO:0030071 - regulation of mitotic metaphase/anaphase transition GO:0032991 - protein-containing complex GO:0035060 - brahma complex GO:0045582 - positive regulation of T cell differentiation GO:0045597 - positive regulation of cell differentiation GO:0045663 - positive regulation of myoblast differentiation GO:0070316 - regulation of G0 to G1 transition GO:0071564 - npBAF complex GO:0071565 - nBAF complex GO:0140092 - bBAF complex GO:1902459 - positive regulation of stem cell population maintenance GO:2000045 - regulation of G1/S transition of mitotic cell cycle GO:2000781 - positive regulation of double-strand break repair GO:2000819 - regulation of nucleotide-excision repair
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1	375
Hs

1	411

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Last updated: 15 Jul 2024