HitPredict

Interactor 1: ACTB (P60710)
Actin, cytoplasmic 1 (Beta-actin) (EC 3.6.4.-) [Cleaved into: Actin, cytoplasmic 1, N-terminally processed]
Gene: ACTB

Interactor 2: RING2 (Q9CQJ4)
E3 ubiquitin-protein ligase RING2 (EC 2.3.2.27) (RING finger protein 1B) (RING1b) (RING finger protein 2) (RING-type E3 ubiquitin transferase RING2)
Gene: Rnf2

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	22496869
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 375 Mm			1 336
+	Mm
		1206351 ACTBL_MOUSE (1-375): 0: 743: 92.80		RING2_MOUSE (1-336): 2.13e-106: 316: 100.00
+	Mm
		929807 ACTG_MOUSE (1-375): 0: 601: 98.93		RING2_MOUSE (1-336): 2.13e-106: 316: 100.00
+	Hs
		929977 ACTG_HUMAN (1-375): 0: 601: 98.93		RING2_HUMAN (1-336): 2.74e-106: 315: 99.70
+	Hs
		717945 POTEE_HUMAN (1-375): 0: 736: 92.00		BMI1_HUMAN (34-332): 2.52e-42: 151: 16.83
+	Hs
		474793 POTEI_HUMAN (1-375): 0: 731: 91.20		BMI1_HUMAN (34-332): 2.52e-42: 151: 16.83
+	Hs
		474817 POTEI_HUMAN (1-375): 0: 731: 91.20		PCGF3_HUMAN (36-334): 2.56e-43: 151: 17.16
+	Hs
		717670 ACTG_HUMAN (1-375): 0: 601: 98.93		BMI1_HUMAN (34-332): 2.52e-42: 151: 16.83
+	Hs
		584915 ACTB_HUMAN (1-375): 0: 603: 100.00		RO52_HUMAN (36-249): 1.63e-36: 139: 13.08
+	Hs
		717643 ACTA_HUMAN (2-375): 0: 591: 94.12		BMI1_HUMAN (34-332): 2.52e-42: 151: 16.83
+	Hs
		891732 ACTB_HUMAN (1-375): 0: 603: 100.00		TRI26_HUMAN (36-283): 2.67e-35: 136: 17.05
+	Hs
		749354 ACTG_HUMAN (1-375): 0: 601: 98.93		BRCA1_HUMAN (36-213): 1.88e-33: 132: 25.93
+	Hs
		933047 ACTS_HUMAN (2-375): 0: 592: 93.58		TRI55_HUMAN (42-318): 5.67e-37: 141: 13.42
+	Hs
		584922 ACTA_HUMAN (2-375): 0: 591: 94.12		RO52_HUMAN (36-249): 1.63e-36: 139: 13.08
+	Hs
		891904 ACTB_HUMAN (1-375): 0: 603: 100.00		TRI58_HUMAN (43-291): 1.53e-30: 122: 15.00
+	Hs
		933049 ACTS_HUMAN (2-375): 0: 592: 93.58		TRIM6_HUMAN (38-292): 1.25e-31: 125: 13.28
+	Hs
		930096 ACTH_HUMAN (2-375): 0: 589: 93.58		TRIM6_HUMAN (38-292): 1.25e-31: 125: 13.28
+	Mm
		929805 ACTG_MOUSE (1-375): 0: 601: 98.93		RN138_MOUSE (34-233): 5.35e-28: 110: 18.00
+	Mm
		932493 ACTC_MOUSE (2-375): 0: 592: 94.12		RN138_MOUSE (34-233): 5.35e-28: 110: 18.00