Protein: MCSP
Sperm mitochondrial-associated cysteine-rich protein

Gene: MCSP, SMCP
Organism: Homo sapiens
Interactions: 77
UniProt ID: P49901

Gene Ontology (top 5):
GO:0005737 - cytoplasm
GO:0005739 - mitochondrion
GO:0007341 - penetration of zona pellucida
GO:0030317 - flagellated sperm motility
GO:0031966 - mitochondrial membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

892221

NT2NA
Notch homolog 2 N-terminal-like protein A

3

1

High-throughput

0.667

High

892231

KR412
Keratin-associated protein 4-12

4

20

High-throughput

0.646

High

685820

KRA59
Keratin-associated protein 5-9

3

20

High-throughput

0.616

High

892192

KR107
Keratin-associated protein 10-7

3

19

High-throughput

0.616

High

892193

KR108
Keratin-associated protein 10-8

3

20

High-throughput

0.616

High

892194

KR109
Keratin-associated protein 10-9

3

20

High-throughput

0.616

High

892200

K1H1
Keratin, type I cuticular Ha1

3

1

High-throughput

0.616

High

892235

KRA92
Keratin-associated protein 9-2

3

20

High-throughput

0.616

High

892236

KR411
Keratin-associated protein 4-11

3

20

High-throughput

0.616

High

892196

DYL1
Dynein light chain 1, cytoplasmic

2

1

High-throughput

0.615

High

457810

MT1B
Metallothionein-1B

2

1

High-throughput

0.606

High

892244

PLS3
Phospholipid scramblase 3

2

1

High-throughput

0.606

High

716410

PRDX5
Peroxiredoxin-5, mitochondrial

2

0

High-throughput

0.580

High

892202

PKHG4
Puratrophin-1

2

0

High-throughput

0.580

High

892203

LCE1D
Late cornified envelope protein 1D

2

0

High-throughput

0.580

High

892214

VASN
Vasorin

2

0

High-throughput

0.580

High

892225

MT1M
Metallothionein-1M

2

0

High-throughput

0.580

High

892243

UBL5
Ubiquitin-like protein 5

2

0

High-throughput

0.580

High

892245

CN119
Uncharacterized protein C14orf119

2

0

High-throughput

0.580

High

300321

KRT34
Keratin, type I cuticular Ha4

2

1

High-throughput

0.553

High

892186

KR121
Keratin-associated protein 12-1

2

1

High-throughput

0.553

High

892197

KRA11
Keratin-associated protein 1-1

2

20

High-throughput

0.553

High

892208

LCE3A
Late cornified envelope protein 3A

2

1

High-throughput

0.553

High

892211

LCE2C
Late cornified envelope protein 2C

2

1

High-throughput

0.553

High

892212

LCE2D
Late cornified envelope protein 2D

2

1

High-throughput

0.553

High

892215

KR511
Keratin-associated protein 5-11

2

20

High-throughput

0.553

High

892218

KRA54
Keratin-associated protein 5-4

2

16

High-throughput

0.553

High

892219

KRA53
Keratin-associated protein 5-3

2

19

High-throughput

0.553

High

892223

KRA13
Keratin-associated protein 1-3

2

20

High-throughput

0.553

High

892229

DYL2
Dynein light chain 2, cytoplasmic

2

1

High-throughput

0.553

High

892232

KRA98
Keratin-associated protein 9-8

2

20

High-throughput

0.553

High

892234

KRA93
Keratin-associated protein 9-3

2

20

High-throughput

0.553

High

892237

KRA41
Keratin-associated protein 4-1

2

20

High-throughput

0.553

High

892239

KRA45
Keratin-associated protein 4-5

2

20

High-throughput

0.553

High

892240

KRA44
Keratin-associated protein 4-4

2

20

High-throughput

0.553

High

892241

KRA42
Keratin-associated protein 4-2

2

20

High-throughput

0.553

High

892242

KRA15
Keratin-associated protein 1-5

2

20

High-throughput

0.553

High

892199

CACO2
Calcium-binding and coiled-coil domain-containing protein 2

1

0

High-throughput

0.549

High

892246

RGS17
Regulator of G-protein signaling 17

1

0

High-throughput

0.549

High

180494

PLS1
Phospholipid scramblase 1

1

1

High-throughput

0.541

High

892233

KRA94
Keratin-associated protein 9-4

1

20

High-throughput

0.523

High

516290

CGB3
Choriogonadotropin subunit beta 3

1

0

High-throughput

0.493

High

516979

NT2NC
Notch homolog 2 N-terminal-like protein C

1

1

High-throughput

0.470

High

892191

KR105
Keratin-associated protein 10-5

1

20

High-throughput

0.470

High

892195

KR10B
Keratin-associated protein 10-11

1

20

High-throughput

0.470

High

892238

KRA47
Keratin-associated protein 4-7

1

20

High-throughput

0.470

High

494

NBPFJ
NBPF family member NBPF19

1

0

High-throughput

0.460

High

892187

KR123
Keratin-associated protein 12-3

1

1

High-throughput

0.439

High

892189

KR101
Keratin-associated protein 10-1

1

20

High-throughput

0.439

High

892190

KR103
Keratin-associated protein 10-3

1

20

High-throughput

0.439

High

892216

KRA57
Keratin-associated protein 5-7

1

19

High-throughput

0.439

High

892210

LCE4A
Late cornified envelope protein 4A

3

0

High-throughput

0.352

High

892217

KRA56
Keratin-associated protein 5-6

3

0

High-throughput

0.352

High

70148

CRTP1
Cysteine-rich tail protein 1

2

0

High-throughput

0.316

High

221325

SPY1
Protein sprouty homolog 1

2

0

High-throughput

0.316

High

289347

CTAG2
Cancer/testis antigen 2

2

0

High-throughput

0.316

High

426063

PPB1
Alkaline phosphatase, placental type

2

0

High-throughput

0.316

High

665916

IBP6
Insulin-like growth factor-binding protein 6

2

0

High-throughput

0.316

High

705279

GRN
Progranulin

2

0

High-throughput

0.316

High

892188

KR124
Keratin-associated protein 12-4

2

0

High-throughput

0.316

High

892204

LCE1E
Late cornified envelope protein 1E

2

0

High-throughput

0.316

High

892205

LCE1F
Late cornified envelope protein 1F

2

0

High-throughput

0.316

High

892206

LCE1A
Late cornified envelope protein 1A

2

0

High-throughput

0.316

High

892207

LCE1B
Late cornified envelope protein 1B

2

0

High-throughput

0.316

High

892209

LCE3B
Late cornified envelope protein 3B

2

0

High-throughput

0.316

High

892213

LCE5A
Late cornified envelope protein 5A

2

0

High-throughput

0.316

High

892220

KRA52
Keratin-associated protein 5-2

2

0

High-throughput

0.316

High

892222

PPR27
Protein phosphatase 1 regulatory subunit 27

2

0

High-throughput

0.316

High

892224

TRI42
Tripartite motif-containing protein 42

2

0

High-throughput

0.316

High

892226

MACOI
Macoilin

2

0

High-throughput

0.316

High

892227

S39A7
Zinc transporter SLC39A7

2

0

High-throughput

0.316

High

892228

PCSK5
Proprotein convertase subtilisin/kexin type 5

2

0

High-throughput

0.316

High

892230

GUCD1
Protein GUCD1

2

0

High-throughput

0.316

High

587026

ITF2
Transcription factor 4

1

0

High-throughput

0.299

High

892198

GOGA2
Golgin subfamily A member 2

1

0

High-throughput

0.299

High

892201

KRA63
Keratin-associated protein 6-3

1

0

High-throughput

0.268

Low

885191

HXA1
Homeobox protein Hox-A1

1

0

High-throughput

0.251

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025