HitPredict

Interactor 1: RAC3 (P60763)
Ras-related C3 botulinum toxin substrate 3 (EC 3.6.5.2) (p21-Rac3)
Gene: RAC3

Interactor 2: LRP10 (Q7Z4F1)
Low-density lipoprotein receptor-related protein 10 (LRP-10)
Gene: LRP10

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 192 Hs			1 713
+	Hs
		925392 RAC1_HUMAN (1-192): 1.92e-84: 249: 92.71		LRP10_HUMAN (17-713): 8.83e-152: 459: 100.00
+	Hs
		1190284 RHOJ_HUMAN (2-190): 2.64e-80: 239: 60.32		LRP10_HUMAN (17-713): 8.83e-152: 459: 100.00
+	Hs
		951112 RHOG_HUMAN (1-192): 2.62e-78: 233: 69.79		LRP10_HUMAN (17-713): 8.83e-152: 459: 100.00
+	Hs
		894166 CDC42_HUMAN (1-192): 3.66e-77: 230: 68.75		LRP10_HUMAN (17-713): 8.83e-152: 459: 100.00
+	Hs
		900633 RHOA_HUMAN (5-192): 2.22e-76: 228: 55.32		LRP10_HUMAN (17-713): 8.83e-152: 459: 100.00
+	Hs
		436374 RHOC_HUMAN (5-192): 2.99e-74: 223: 54.79		LRP10_HUMAN (17-713): 8.83e-152: 459: 100.00
+	Hs
		564591 RHOQ_HUMAN (4-189): 1.4e-73: 222: 63.49		LRP10_HUMAN (17-713): 8.83e-152: 459: 100.00
+	Hs
		254256 RAC1_HUMAN (1-192): 1.92e-84: 249: 92.71		LRP4_HUMAN (249-518): 3.93e-29: 126: 18.86
+	Hs
		258305 RAC1_HUMAN (1-192): 1.92e-84: 249: 92.71		LRP5_HUMAN (130-297): 8.23e-22: 103: 8.72
+	Hs
		258292 RAC2_HUMAN (1-192): 6.96e-81: 240: 88.54		LRP5_HUMAN (130-297): 8.23e-22: 103: 8.72
+	Hs
		258347 RHOJ_HUMAN (2-190): 2.64e-80: 239: 60.32		LRP5_HUMAN (130-297): 8.23e-22: 103: 8.72
+	Hs
		258302 RAC3_HUMAN (1-192): 5.54e-79: 235: 100.00		LRP5_HUMAN (130-297): 8.23e-22: 103: 8.72
+	Hs
		258303 CDC42_HUMAN (1-192): 3.66e-77: 230: 68.75		LRP5_HUMAN (130-297): 8.23e-22: 103: 8.72
+	Hs
		258304 RHOA_HUMAN (5-192): 2.22e-76: 228: 55.32		LRP5_HUMAN (130-297): 8.23e-22: 103: 8.72
+	Hs
		270329 RHOJ_HUMAN (2-190): 2.64e-80: 239: 60.32		LRP6_HUMAN (78-229): 5.54e-15: 81.5: 14.94
+	Hs
		270285 RAC3_HUMAN (1-192): 5.54e-79: 235: 100.00		LRP6_HUMAN (78-229): 5.54e-15: 81.5: 14.94
+	Hs
		925190 RAC1_HUMAN (1-192): 1.92e-84: 249: 92.71		LRP2_HUMAN (344-521): 1.01e-09: 64.6: 20.33
+	Hs
		893898 CDC42_HUMAN (1-192): 3.66e-77: 230: 68.75		LRP2_HUMAN (344-521): 1.01e-09: 64.6: 20.33
+	Hs
		900376 RHOA_HUMAN (5-192): 2.22e-76: 228: 55.32		LRP2_HUMAN (344-521): 1.01e-09: 64.6: 20.33
+	Hs
		564477 RHOQ_HUMAN (4-189): 1.4e-73: 222: 63.49		LRP2_HUMAN (344-521): 1.01e-09: 64.6: 20.33