HitPredict

Interactor 1: RAC3 (P60763)
Ras-related C3 botulinum toxin substrate 3 (EC 3.6.5.2) (p21-Rac3)
Gene: RAC3

Interactor 2: MACOI (Q8N5G2)
Macoilin (Macoilin-1) (Transmembrane protein 57)
Gene: MACO1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 192 Hs			1 664
+	Hs
		545494 RAC2_HUMAN (1-192): 6.96e-81: 240: 88.54		MACOI_HUMAN (1-664): 2.34e-140: 426: 100.00
+	Hs
		951151 RHOG_HUMAN (1-192): 2.62e-78: 233: 69.79		MACOI_HUMAN (1-664): 2.34e-140: 426: 100.00
+	Hs
		894211 CDC42_HUMAN (1-192): 3.66e-77: 230: 68.75		MACOI_HUMAN (1-664): 2.34e-140: 426: 100.00
+	Hs
		545482 RAC2_HUMAN (1-192): 6.96e-81: 240: 88.54		MY18B_HUMAN (177-640): 2.83e-28: 123: 15.82
+	Hs
		925488 RAC1_HUMAN (1-192): 1.92e-84: 249: 92.71		MY18A_HUMAN (179-648): 2.66e-20: 98.3: 10.97
+	Hs
		545537 RAC2_HUMAN (1-192): 6.96e-81: 240: 88.54		MY18A_HUMAN (179-648): 2.66e-20: 98.3: 10.97
+	Hs
		892521 RAC3_HUMAN (1-192): 5.54e-79: 235: 100.00		MY18A_HUMAN (179-648): 2.66e-20: 98.3: 10.97
+	Mm
		823530 RAC1_MOUSE (1-192): 1.92e-84: 249: 92.71		CTRO_MOUSE (284-664): 1.45e-14: 79.8: 11.26
+	Hs
		724757 RAC1_HUMAN (1-192): 1.92e-84: 249: 92.71		MYH9_HUMAN (164-553): 5.97e-12: 71.3: 9.44
+	Hs
		148653 RAC1_HUMAN (1-192): 1.92e-84: 249: 92.71		CTRO_HUMAN (313-648): 7.96e-12: 70.9: 10.17
+	Hs
		925344 RAC1_HUMAN (1-192): 1.92e-84: 249: 92.71		MRCKA_HUMAN (180-613): 6.09e-09: 61.8: 13.72
+	Mm
		823529 CDC42_MOUSE (1-192): 3.66e-77: 230: 68.75		CTRO_MOUSE (284-664): 1.45e-14: 79.8: 11.26
+	Hs
		724776 RHOG_HUMAN (1-192): 2.62e-78: 233: 69.79		MYH9_HUMAN (164-553): 5.97e-12: 71.3: 9.44
+	Hs
		545430 RAC2_HUMAN (1-192): 6.96e-81: 240: 88.54		MRCKA_HUMAN (180-613): 6.09e-09: 61.8: 13.72
+	Hs
		1137905 RHOJ_HUMAN (2-190): 2.64e-80: 239: 60.32		MRCKA_HUMAN (180-613): 6.09e-09: 61.8: 13.72
+	Hs
		892423 RAC3_HUMAN (1-192): 5.54e-79: 235: 100.00		MRCKA_HUMAN (180-613): 6.09e-09: 61.8: 13.72
+	Hs
		725138 RHOG_HUMAN (1-192): 2.62e-78: 233: 69.79		MYH10_HUMAN (382-660): 4.67e-09: 62.1: 9.68
+	Hs
		951069 RHOG_HUMAN (1-192): 2.62e-78: 233: 69.79		MRCKA_HUMAN (180-613): 6.09e-09: 61.8: 13.72
+	Hs
		725125 CDC42_HUMAN (1-192): 3.66e-77: 230: 68.75		MYH10_HUMAN (382-660): 4.67e-09: 62.1: 9.68
+	Hs
		894116 CDC42_HUMAN (1-192): 3.66e-77: 230: 68.75		MRCKA_HUMAN (180-613): 6.09e-09: 61.8: 13.72