Interactor 1: IF4A1 (P60842)
Eukaryotic initiation factor 4A-I (eIF-4A-I) (eIF4A-I) (EC 3.6.4.13) (ATP-dependent RNA helicase eIF4A-1)
Gene: EIF4A1
Interactor 2: IF4G1 (Q04637)
Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G 1) (eIF-4G1) (p220)
Gene: EIF4G1
Species: Homo sapiens
Source: mint
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.97 | 1.00 | 0.988 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 9418880, 24768540, 27864334, 16648488, 16541103, 24248602, 28514442, 17353931, 29395067, 33961781, 35235311, 37071682, 17053147, 22586265, 18606994, 23478064, 19203580, 11408474, 23023399, 16932749 |
| Identification Methods | affinity chromatography technology, proximity labelling technology, cross-linking study, dynamic light scattering, molecular sieving, isothermal titration calorimetry, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, surface plasmon resonance, nuclear magnetic resonance and 2 others
more... |
| Interaction Type | physical association, direct interaction, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | DEAD~MA3, DEAD~MIF4G, Helicase_C~MA3, Helicase_C~MIF4G |
| Common GO terms | GO:0003723 - RNA binding GO:0003729 - mRNA binding GO:0003743 - translation initiation factor activity GO:0005524 - ATP binding GO:0005737 - cytoplasm and 5 others more... |
| Homologous interactions | 20 |
Homologous interactions (Top 20)
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
