HitPredict

Interactor 1: S10AA (P60903)
Protein S100-A10 (Calpactin I light chain) (Calpactin-1 light chain) (Cellular ligand of annexin II) (S100 calcium-binding protein A10) (p10 protein) (p11)
Gene: S100A10

Interactor 2: TRPM4 (Q8TD43)
Transient receptor potential cation channel subfamily M member 4 (hTRPM4) (Calcium-activated non-selective cation channel 1) (Long transient receptor potential channel 4) (LTrpC-4) (LTrpC4) (Melastatin-4)
Gene: TRPM4

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	31837246
Identification Methods	fluorescence polarization spectroscopy
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005509 - calcium ion binding GO:0005886 - plasma membrane
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 97 Hs			1 1214
+	Hs
		615221 S10A1_HUMAN (1-91): 7.71e-34: 113: 45.75		TRPM4_HUMAN (1-1214): 0: 1243: 100.00
+	Hs
		685179 S10AB_HUMAN (2-89): 4.9e-32: 109: 38.46		TRPM4_HUMAN (1-1214): 0: 1243: 100.00
+	Hs
		639026 S100P_HUMAN (3-87): 5.8e-31: 106: 45.46		TRPM4_HUMAN (1-1214): 0: 1243: 100.00
+	Hs
		416480 S10A9_HUMAN (3-96): 8.76e-29: 101: 29.59		TRPM4_HUMAN (1-1214): 0: 1243: 100.00
+	Hs
		642972 S10A4_HUMAN (1-87): 5.03e-29: 101: 35.56		TRPM4_HUMAN (1-1214): 0: 1243: 100.00
+	Hs
		707382 S10A3_HUMAN (1-89): 7.96e-29: 101: 27.17		TRPM4_HUMAN (1-1214): 0: 1243: 100.00
+	Hs
		661361 S10A2_HUMAN (1-87): 6.38e-28: 98.8: 36.67		TRPM4_HUMAN (1-1214): 0: 1243: 100.00
+	Hs
		380818 S100B_HUMAN (3-87): 2.3e-26: 94.6: 37.50		TRPM4_HUMAN (1-1214): 0: 1243: 100.00
+	Hs
		707352 S10A5_HUMAN (1-92): 1.15e-23: 88: 30.53		TRPM4_HUMAN (1-1214): 0: 1243: 100.00
+	Hs
		396768 S10A8_HUMAN (1-93): 1.69e-23: 87.6: 25.00		TRPM4_HUMAN (1-1214): 0: 1243: 100.00
+	Hs
		416665 S10A6_HUMAN (1-88): 2.47e-23: 86.9: 25.28		TRPM4_HUMAN (1-1214): 0: 1243: 100.00
+	Hs
		1254558 S10AE_HUMAN (3-81): 4.74e-19: 76.5: 28.40		TRPM4_HUMAN (1-1214): 0: 1243: 100.00