HitPredict

Interactor 1: CDC42 (P60953)
Cell division control protein 42 homolog (EC 3.6.5.2) (G25K GTP-binding protein)
Gene: CDC42

Interactor 2: PPIA (P62937)
Peptidyl-prolyl cis-trans isomerase A (PPIase A) (EC 5.2.1.8) (Cyclophilin A) (Cyclosporin A-binding protein) (Rotamase A) [Cleaved into: Peptidyl-prolyl cis-trans isomerase A, N-terminally processed]
Gene: PPIA

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005925 - focal adhesion GO:0016020 - membrane GO:0032991 - protein-containing complex and 1 others more... GO:0070062 - extracellular exosome
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 191 Hs			1 165
+	Hs
		923786 RHOJ_HUMAN (2-188): 2.67e-85: 252: 64.17		PPIA_HUMAN (1-165): 2.77e-91: 264: 100.00
+	Hs
		923633 RAC1_HUMAN (1-191): 1.75e-84: 249: 70.31		PPIA_HUMAN (1-165): 2.77e-91: 264: 100.00
+	Hs
		673675 RHOG_HUMAN (1-191): 7.59e-82: 242: 60.73		PPIF_HUMAN (3-164): 6.26e-92: 267: 76.54
+	Hs
		923641 RHOG_HUMAN (1-191): 7.59e-82: 242: 60.73		PPIA_HUMAN (1-165): 2.77e-91: 264: 100.00
+	Hs
		900356 RHOA_HUMAN (5-191): 3.88e-81: 240: 53.48		PPIA_HUMAN (1-165): 2.77e-91: 264: 100.00
+	Hs
		545308 RAC2_HUMAN (1-191): 1.49e-80: 239: 68.75		PPIA_HUMAN (1-165): 2.77e-91: 264: 100.00
+	Hs
		901053 RHOA_HUMAN (5-191): 3.88e-81: 240: 53.48		PPIE_HUMAN (2-163): 2.08e-88: 262: 67.28
+	Hs
		436246 RHOC_HUMAN (5-191): 3.64e-79: 235: 52.41		PPIA_HUMAN (1-165): 2.77e-91: 264: 100.00
+	Hs
		892306 RAC3_HUMAN (1-177): 2.36e-78: 233: 72.32		PPIA_HUMAN (1-165): 2.77e-91: 264: 100.00
+	Hs
		923719 RHOU_HUMAN (4-186): 1.03e-72: 221: 58.82		PPIA_HUMAN (1-165): 2.77e-91: 264: 100.00