HitPredict

Interactor 1: CDC42 (P60953)
Cell division control protein 42 homolog (EC 3.6.5.2) (G25K GTP-binding protein)
Gene: CDC42

Interactor 2: ANK3 (Q12955)
Ankyrin-3 (ANK-3) (Ankyrin-G)
Gene: ANK3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Ank~Ras, Ank_2~Ras, Ank_4~Ras
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0043005 - neuron projection
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 191 Hs			1 4377
+	Hs
		925238 RAC1_HUMAN (1-191): 1.75e-84: 249: 70.31		ANK3_HUMAN (1-4377): 0: 1944: 100.00
+	Hs
		950953 RHOG_HUMAN (1-191): 7.59e-82: 242: 60.73		ANK3_HUMAN (1-4377): 0: 1944: 100.00
+	Hs
		900423 RHOA_HUMAN (5-191): 3.88e-81: 240: 53.48		ANK3_HUMAN (1-4377): 0: 1944: 100.00
+	Hs
		1021421 RHOU_HUMAN (4-186): 1.03e-72: 221: 58.82		ANK3_HUMAN (1-4377): 0: 1944: 100.00
+	Hs
		925204 RAC1_HUMAN (1-191): 1.75e-84: 249: 70.31		ANK2_HUMAN (3012-4350): 1.52e-22: 110: 9.15