Protein: NMDE2
Glutamate receptor ionotropic, NMDA 2B (GluN2B) (Glutamate [NMDA] receptor subunit epsilon-2) (N-methyl D-aspartate receptor subtype 2B) (NMDAR2B) (NR2B) (N-methyl-D-aspartate receptor subunit 3) (NR3) (hNR3)

Gene: NMDE2, GRIN2B
Organism: Homo sapiens
Interactions: 54
UniProt ID: Q13224

Gene Ontology (top 5):
GO:0001540 - amyloid-beta binding
GO:0004972 - NMDA glutamate receptor activity
GO:0005737 - cytoplasm
GO:0005764 - lysosome
GO:0005770 - late endosome

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

984258

NMDZ1
Glutamate receptor ionotropic, NMDA 1

9

20

Small-scale

0.966

High

1018889

NMDE1
Glutamate receptor ionotropic, NMDA 2A

3

18

Small-scale

0.853

High

942337

DLG4
Disks large homolog 4

18

20

Small-scale

0.765

High

1021485

DLG1
Disks large homolog 1

6

20

Small-scale

0.721

High

1028145

DLG3
Disks large homolog 3

5

20

Small-scale

0.713

High

1028155

KCC2A
Calcium/calmodulin-dependent protein kinase type II subunit alpha

4

15

Small-scale

0.702

High

1028140

DLG2
Disks large homolog 2

3

20

Small-scale

0.648

High

1028135

NMDE2
Glutamate receptor ionotropic, NMDA 2B

1

18

Small-scale

0.647

High

1028143

NMD3A
Glutamate receptor ionotropic, NMDA 3A

1

18

Small-scale

0.618

High

412171

FYN
Tyrosine-protein kinase Fyn

2

6

Small-scale

0.602

High

1028136

KCC2G
Calcium/calmodulin-dependent protein kinase type II subunit gamma

2

15

Small-scale

0.595

High

394650

A4
Amyloid-beta precursor protein

2

9

Small-scale

0.584

High

338365

EGFR
Epidermal growth factor receptor

1

9

Small-scale

0.578

High

64702

RHG32
Rho GTPase-activating protein 32

1

1

Small-scale

0.573

High

1028138

RGRF1
Ras-specific guanine nucleotide-releasing factor 1

1

10

Small-scale

0.573

High

1028147

MIB2
E3 ubiquitin-protein ligase MIB2

1

4

Small-scale

0.561

High

1028152

LIN7B
Protein lin-7 homolog B

1

20

Small-scale

0.561

High

1028137

SPTN1
Spectrin alpha chain, non-erythrocytic 1

1

14

Small-scale

0.550

High

158278

LIN7A
Protein lin-7 homolog A

1

20

Small-scale

0.501

High

441195

PTPRC
Receptor-type tyrosine-protein phosphatase C

1

9

High-throughput

0.501

High

566381

KPCA
Protein kinase C alpha type

1

12

Small-scale

0.501

High

616915

PTPRB
Receptor-type tyrosine-protein phosphatase beta

1

8

High-throughput

0.501

High

617106

PTPRG
Receptor-type tyrosine-protein phosphatase gamma

1

9

High-throughput

0.501

High

931616

CSK2B
Casein kinase II subunit beta

1

1

Small-scale

0.501

High

934133

CSK21
Casein kinase II subunit alpha

1

5

Small-scale

0.501

High

983478

PTN12
Tyrosine-protein phosphatase non-receptor type 12

1

13

High-throughput

0.501

High

1020091

PTPRJ
Receptor-type tyrosine-protein phosphatase eta

1

9

High-throughput

0.501

High

1028139

SCRIB
Protein scribble homolog

1

20

High-throughput

0.501

High

1028149

ERBIN
Erbin

1

4

Small-scale

0.501

High

1028154

EXOC7
Exocyst complex component 7

1

3

Small-scale

0.501

High

1028142

MAGI3
Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 3

1

20

Small-scale

0.494

High

725650

ACTN2
Alpha-actinin-2

1

9

Small-scale

0.481

High

1028148

AP2M1
AP-2 complex subunit mu

1

7

Small-scale

0.481

High

1028151

AP1M1
AP-1 complex subunit mu-1

1

7

Small-scale

0.481

High

227344

PRKN
E3 ubiquitin-protein ligase parkin

1

5

Small-scale

0.479

High

441497

MET
Hepatocyte growth factor receptor

1

8

Small-scale

0.479

High

611431

NR4A1
Nuclear receptor subfamily 4immunitygroup A member 1

1

2

Small-scale

0.479

High

665594

EPHB2
Ephrin type-B receptor 2

1

3

Small-scale

0.479

High

742271

SYUA
Alpha-synuclein

1

1

Small-scale

0.479

High

792771

EAA3
Excitatory amino acid transporter 3

1

4

Small-scale

0.479

High

849931

APLP1
Amyloid beta precursor like protein 1

1

9

Small-scale

0.479

High

987502

APLP2
Amyloid beta precursor like protein 2

1

9

Small-scale

0.479

High

1028141

DPYL2
Dihydropyrimidinase-related protein 2

1

7

Small-scale

0.479

High

1028144

NETO1
Neuropilin and tolloid-like protein 1

1

7

Small-scale

0.479

High

1028146

EXOC4
Exocyst complex component 4

1

4

Small-scale

0.479

High

1028150

SGMR1
Sigma non-opioid intracellular receptor 1

1

1

Small-scale

0.479

High

929436

RACK1
Small ribosomal subunit protein RACK1

1

0

Small-scale

0.458

High

944674

MAP1A
Microtubule-associated protein 1A

1

0

Small-scale

0.458

High

1028153

KDM5B
Lysine-specific demethylase 5B

1

0

Small-scale

0.458

High

586719

CSK22
Casein kinase II subunit alpha'

1

5

Small-scale

0.457

High

119716

AP4M1
AP-4 complex subunit mu-1

1

7

Small-scale

0.439

High

101695

F8VWT9
HECT domain E3 ubiquitin protein ligase 4

1

9

Small-scale

0.437

High

237968

EXOC3
Exocyst complex component 3

1

2

Small-scale

0.437

High


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Last updated: 15 Jul 2024