HitPredict

Interactor 1: CDC42 (P60953)
Cell division control protein 42 homolog (EC 3.6.5.2) (G25K GTP-binding protein)
Gene: CDC42

Interactor 2: SEPT6 (Q14141)
Septin-6
Gene: SEPTIN6

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003924 - GTPase activity GO:0005525 - GTP binding GO:0030496 - midbody
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 191 Hs			1 434
+	Hs
		1049000 RHOU_HUMAN (4-186): 1.03e-72: 221: 58.82		SEPT6_HUMAN (1-434): 0: 607: 100.00
+	Hs
		1330963 RHOJ_HUMAN (2-188): 2.67e-85: 252: 64.17		SEP10_HUMAN (12-431): 0: 573: 71.67
+	Hs
		894272 CDC42_HUMAN (1-191): 4.96e-82: 243: 100.00		SEPT8_HUMAN (1-427): 0: 581: 76.22
+	Hs
		925687 RAC1_HUMAN (1-191): 1.75e-84: 249: 70.31		SEP10_HUMAN (12-431): 0: 573: 71.67
+	Hs
		894532 CDC42_HUMAN (1-191): 4.96e-82: 243: 100.00		SEP10_HUMAN (12-431): 0: 573: 71.67
+	Hs
		894495 CDC42_HUMAN (1-191): 4.96e-82: 243: 100.00		SEP11_HUMAN (3-400): 0: 548: 83.92
+	Hs
		894054 CDC42_HUMAN (1-191): 4.96e-82: 243: 100.00		SEPT7_HUMAN (2-425): 0: 529: 38.94
+	Hs
		894021 CDC42_HUMAN (1-191): 4.96e-82: 243: 100.00		SEPT2_HUMAN (16-348): 1.31e-159: 456: 39.77
+	Hs
		951004 RHOG_HUMAN (1-191): 7.59e-82: 242: 60.73		SEPT2_HUMAN (16-348): 1.31e-159: 456: 39.77
+	Hs
		894560 CDC42_HUMAN (1-191): 4.96e-82: 243: 100.00		SEPT9_HUMAN (9-323): 2.65e-152: 445: 39.94