HitPredict

Interactor 1: CDC42 (P60953)
Cell division control protein 42 homolog (EC 3.6.5.2) (G25K GTP-binding protein)
Gene: CDC42

Interactor 2: ARHG7 (Q14155)
Rho guanine nucleotide exchange factor 7 (Beta-Pix) (COOL-1) (PAK-interacting exchange factor beta) (p85)
Gene: ARHGEF7

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.86 1.00 0.930

The method score is based on:

Property Details
Experiments 31478661, 31871319, 14505571, 25150978, 16983070
Identification Methods pull down, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains PH~Ras, Ras~RhoGEF
Common GO terms GO:0005737 - cytoplasm
GO:0005813 - centrosome
GO:0005829 - cytosol
GO:0005925 - focal adhesion
GO:0007030 - Golgi organization
and 5 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 191
Hs

1 803
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024