Protein: CA174
UPF0688 protein C1orf174

Gene: CA174, C1orf174
Organism: Homo sapiens
Interactions: 92
UniProt ID: Q8IYL3

Gene Ontology (top 5):
GO:0005654 - nucleoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1315226

PDK1L
Serine/threonine-protein kinase PDIK1L

7

1

High-throughput

0.751

High

1315233

STK35
Serine/threonine-protein kinase 35

4

1

High-throughput

0.697

High

1104610

IKZF1
DNA-binding protein Ikaros

4

0

High-throughput

0.668

High

1315260

PARP2
Poly [ADP-ribose] polymerase 2

2

0

High-throughput

0.576

High

1315256

TE2IP
Telomeric repeat-binding factor 2-interacting protein 1

1

0

High-throughput

0.549

High

230057

SAHH2
S-adenosylhomocysteine hydrolase-like protein 1

2

1

High-throughput

0.549

High

277739

H2AY
Core histone macro-H2A.1

1

3

High-throughput

0.536

High

591725

H2AX
Histone H2AX

1

3

High-throughput

0.536

High

1315268

RRP44
Exosome complex exonuclease RRP44

1

1

High-throughput

0.536

High

1272479

CSN6
COP9 signalosome complex subunit 6

1

0

High-throughput

0.518

High

1315237

KAT5
Histone acetyltransferase KAT5

1

0

High-throughput

0.518

High

853338

CBX5
Chromobox protein homolog 5

1

0

High-throughput

0.513

High

1032836

XPC
DNA repair protein complementing XP-C cells

1

0

High-throughput

0.513

High

1307373

RIOX2
Ribosomal oxygenase 2

1

0

High-throughput

0.513

High

1315251

EGLN3
Prolyl hydroxylase EGLN3

1

0

High-throughput

0.513

High

502424

H2A1
Histone H2A type 1

1

2

High-throughput

0.489

High

664066

PRTN3
Myeloblastin

1

1

High-throughput

0.489

High

1307271

H2A2B
Histone H2A type 2-B

1

2

High-throughput

0.489

High

1315240

SAHH3
Adenosylhomocysteinase 3

1

1

High-throughput

0.489

High

728326

AKT1
RAC-alpha serine/threonine-protein kinase

1

0

Small-scale

0.480

High

998528

H31
Histone H3.1

1

1

High-throughput

0.479

High

1137846

TNIP1
TNFAIP3-interacting protein 1

1

1

High-throughput

0.479

High

1232446

Q6FHY5
MEOX2 protein

1

1

High-throughput

0.470

High

173047

XPO1
Exportin-1

1

0

High-throughput

0.458

High

315766

RECQ4
ATP-dependent DNA helicase Q4

1

0

High-throughput

0.458

High

904920

MECP2
Methyl-CpG-binding protein 2

1

0

High-throughput

0.458

High

979965

H4
Histone H4

1

0

High-throughput

0.458

High

980915

H2B1C
Histone H2B type 1-C/E/F/G/I

1

0

High-throughput

0.458

High

1045495

TF65
Transcription factor p65

1

0

High-throughput

0.458

High

1313252

SMC5
Structural maintenance of chromosomes protein 5

1

0

High-throughput

0.458

High

1315236

ESR2
Estrogen receptor beta

1

0

High-throughput

0.458

High

1315259

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

243674

SMCA5
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5

1

1

High-throughput

0.445

High

703347

SMCA1
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 1

1

1

High-throughput

0.445

High

1216224

H37
Histone H3-7

1

1

High-throughput

0.445

High

1219408

TUT7
Terminal uridylyltransferase 7

1

1

High-throughput

0.445

High

1313901

DHX37
Probable ATP-dependent RNA helicase DHX37

1

2

High-throughput

0.445

High

1315246

UHRF1
E3 ubiquitin-protein ligase UHRF1

1

1

High-throughput

0.445

High

1315247

HELZ2
3'-5' exoribonuclease HELZ2

1

1

High-throughput

0.445

High

1315262

BAZ1B
Tyrosine-protein kinase BAZ1B

1

2

High-throughput

0.445

High

1315265

ZMYD8
MYND-type zinc finger-containing chromatin reader ZMYND8

1

2

High-throughput

0.445

High

893997

MEOX2
Homeobox protein MOX-2

1

1

High-throughput

0.439

High

1141211

BRD3
Bromodomain-containing protein 3

1

1

High-throughput

0.437

High

355558

NSD2
Histone-lysine N-methyltransferase NSD2

1

0

High-throughput

0.426

High

697420

DCK
Deoxycytidine kinase

1

0

High-throughput

0.426

High

1006534

SRPK2
SRSF protein kinase 2

1

0

High-throughput

0.426

High

1179323

TSR1
Pre-rRNA-processing protein TSR1 homolog

1

0

High-throughput

0.426

High

1228590

SPT2
Protein SPT2 homolog

1

0

High-throughput

0.426

High

1277181

POGZ
Pogo transposable element with ZNF domain

1

0

High-throughput

0.426

High

1315227

ZCHC9
Zinc finger CCHC domain-containing protein 9

1

0

High-throughput

0.426

High

1315229

ZC3H8
Zinc finger CCCH domain-containing protein 8

1

0

High-throughput

0.426

High

1315232

DDX55
ATP-dependent RNA helicase DDX55

1

0

High-throughput

0.426

High

1315238

PINX1
PIN2/TERF1-interacting telomerase inhibitor 1

1

0

High-throughput

0.426

High

1315239

TRM61
tRNA

1

0

High-throughput

0.426

High

1315241

CHAP1
Chromosome alignment-maintaining phosphoprotein 1

1

0

High-throughput

0.426

High

1315243

NSUN5
28S rRNA

1

0

High-throughput

0.426

High

1315244

F111A
Serine protease FAM111A

1

0

High-throughput

0.426

High

1315249

DHX33
ATP-dependent RNA helicase DHX33

1

0

High-throughput

0.426

High

1315252

MET17
Ribosome assembly protein METTL17, mitochondrial

1

0

High-throughput

0.426

High

1315254

DDX28
Probable ATP-dependent RNA helicase DDX28

1

0

High-throughput

0.426

High

1315258

UBP36
Ubiquitin carboxyl-terminal hydrolase 36

1

0

High-throughput

0.426

High

1315263

TRM6
tRNA

1

0

High-throughput

0.426

High

1315264

ZN346
Zinc finger protein 346

1

0

High-throughput

0.426

High

1315267

HPSE
Heparanase

1

0

High-throughput

0.426

High

1149441

SKI2
Superkiller complex protein 2

1

1

High-throughput

0.407

High

1204837

DDX6L
Probable ATP-dependent RNA helicase DDX60-like

1

1

High-throughput

0.407

High

1240447

DHX57
Putative ATP-dependent RNA helicase DHX57

1

2

High-throughput

0.407

High

1315231

PAPD5
Terminal nucleotidyltransferase 4B

1

1

High-throughput

0.407

High

1315250

YTDC2
3'-5' RNA helicase YTHDC2

1

2

High-throughput

0.407

High

1315261

BAZ2A
Bromodomain adjacent to zinc finger domain protein 2A

1

1

High-throughput

0.407

High

688066

EF1G
Elongation factor 1-gamma

1

0

High-throughput

0.282

High

1315230

GOLM1
Golgi membrane protein 1

1

0

High-throughput

0.282

High

455654

KLK3
Prostate-specific antigen

1

0

High-throughput

0.279

Low

916180

BIEA
Biliverdin reductase A

1

0

High-throughput

0.279

Low

1315248

TPK1
Thiamine pyrophosphokinase 1

1

0

High-throughput

0.279

Low

1315255

LIN7C
Protein lin-7 homolog C

1

0

High-throughput

0.279

Low

1315257

PALS2
Protein PALS2

1

0

High-throughput

0.279

Low

772897

MYH9
Myosin-9

1

0

High-throughput

0.269

Low

422542

A4
Amyloid-beta precursor protein

1

0

High-throughput

0.261

Low

401123

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

0

High-throughput

0.249

Low

1024694

VIGLN
Vigilin

1

0

High-throughput

0.249

Low

134333

RPOM
DNA-directed RNA polymerase, mitochondrial

1

0

High-throughput

0.232

Low

1178703

MTHSD
Methenyltetrahydrofolate synthase domain-containing protein

1

0

High-throughput

0.232

Low

1308425

ERI1
3'-5' exoribonuclease 1

1

0

High-throughput

0.232

Low

1315228

SRBD1
S1 RNA-binding domain-containing protein 1

1

0

High-throughput

0.232

Low

1315234

TFB1M
Dimethyladenosine transferase 1, mitochondrial

1

0

High-throughput

0.232

Low

1315235

ZN592
Zinc finger protein 592

1

0

High-throughput

0.232

Low

1315242

PWP2A
PWWP domain-containing protein 2A

1

0

High-throughput

0.232

Low

1315245

TEFM
Transcription elongation factor, mitochondrial

1

0

High-throughput

0.232

Low

1315253

MRM3
rRNA methyltransferase 3, mitochondrial

1

0

High-throughput

0.232

Low

1315266

UTP16
U3 small nucleolar RNA-associated protein NOL7

1

0

High-throughput

0.232

Low

1315269

YBOX2
Y-box-binding protein 2

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025