HitPredict

Interactor 1: CDC42 (P60953)
Cell division control protein 42 homolog (EC 3.6.5.2) (G25K GTP-binding protein)
Gene: CDC42

Interactor 2: FLOT2 (Q14254)
Flotillin-2 (Epidermal surface antigen) (ESA) (Membrane component chromosome 17 surface marker 1)
Gene: FLOT2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0005925 - focal adhesion GO:0016020 - membrane GO:0070062 - extracellular exosome GO:0098978 - glutamatergic synapse
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 191 Hs			1 428
+	Hs
		564528 RHOQ_HUMAN (4-187): 7.35e-91: 266: 67.94		FLOT2_HUMAN (1-428): 5.86e-158: 454: 100.00
+	Hs
		1052484 RHOJ_HUMAN (2-188): 2.67e-85: 252: 64.17		FLOT2_HUMAN (1-428): 5.86e-158: 454: 100.00
+	Hs
		925277 RAC1_HUMAN (1-191): 1.75e-84: 249: 70.31		FLOT2_HUMAN (1-428): 5.86e-158: 454: 100.00
+	Hs
		950993 RHOG_HUMAN (1-191): 7.59e-82: 242: 60.73		FLOT2_HUMAN (1-428): 5.86e-158: 454: 100.00
+	Hs
		900464 RHOA_HUMAN (5-191): 3.88e-81: 240: 53.48		FLOT2_HUMAN (1-428): 5.86e-158: 454: 100.00
+	Hs
		279430 RHOQ_HUMAN (4-187): 7.35e-91: 266: 67.94		FLOT1_HUMAN (5-417): 1.06e-121: 362: 47.49
+	Hs
		279709 RHOJ_HUMAN (2-188): 2.67e-85: 252: 64.17		FLOT1_HUMAN (5-417): 1.06e-121: 362: 47.49
+	Hs
		279505 RAC1_HUMAN (1-191): 1.75e-84: 249: 70.31		FLOT1_HUMAN (5-417): 1.06e-121: 362: 47.49
+	Hs
		279496 CDC42_HUMAN (1-191): 4.96e-82: 243: 100.00		FLOT1_HUMAN (5-417): 1.06e-121: 362: 47.49
+	Hs
		279511 RHOG_HUMAN (1-191): 7.59e-82: 242: 60.73		FLOT1_HUMAN (5-417): 1.06e-121: 362: 47.49
+	Hs
		279500 RHOA_HUMAN (5-191): 3.88e-81: 240: 53.48		FLOT1_HUMAN (5-417): 1.06e-121: 362: 47.49
+	Hs
		279425 RAC2_HUMAN (1-191): 1.49e-80: 239: 68.75		FLOT1_HUMAN (5-417): 1.06e-121: 362: 47.49
+	Hs
		564417 RHOQ_HUMAN (4-187): 7.35e-91: 266: 67.94		STOM_HUMAN (4-231): 6.87e-36: 135: 16.59
+	Hs
		646300 RHOJ_HUMAN (2-188): 2.67e-85: 252: 64.17		STOM_HUMAN (4-231): 6.87e-36: 135: 16.59
+	Hs
		646166 RAC1_HUMAN (1-191): 1.75e-84: 249: 70.31		STOM_HUMAN (4-231): 6.87e-36: 135: 16.59
+	Hs
		646157 CDC42_HUMAN (1-191): 4.96e-82: 243: 100.00		STOM_HUMAN (4-231): 6.87e-36: 135: 16.59
+	Hs
		646171 RHOG_HUMAN (1-191): 7.59e-82: 242: 60.73		STOM_HUMAN (4-231): 6.87e-36: 135: 16.59
+	Hs
		646160 RHOA_HUMAN (5-191): 3.88e-81: 240: 53.48		STOM_HUMAN (4-231): 6.87e-36: 135: 16.59
+	Hs
		545212 RAC2_HUMAN (1-191): 1.49e-80: 239: 68.75		STOM_HUMAN (4-231): 6.87e-36: 135: 16.59
+	Hs
		951448 RHOG_HUMAN (1-191): 7.59e-82: 242: 60.73		STML2_HUMAN (26-220): 1.09e-16: 83: 19.90