HitPredict

Interactor 1: CDC42 (P60953)
Cell division control protein 42 homolog (EC 3.6.5.2) (G25K GTP-binding protein)
Gene: CDC42

Interactor 2: FLNC (Q14315)
Filamin-C (FLN-C) (FLNc) (ABP-280-like protein) (ABP-L) (Actin-binding-like protein) (Filamin-2) (Gamma-filamin)
Gene: FLNC

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	31478661
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0005925 - focal adhesion
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 191 Hs			1 2725
+	Hs
		598063 RHOG_HUMAN (1-191): 7.59e-82: 242: 60.73		FLNA_HUMAN (167-2725): 0: 1226: 35.27
+	Hs
		261241 RAC1_HUMAN (1-191): 1.75e-84: 249: 70.31		FLNB_HUMAN (146-2725): 0: 1198: 35.18
+	Hs
		564483 RHOQ_HUMAN (4-187): 7.35e-91: 266: 67.94		SPTB2_HUMAN (26-266): 1.26e-100: 365: 38.12
+	Hs
		963416 RHOJ_HUMAN (2-188): 2.67e-85: 252: 64.17		SPTB2_HUMAN (26-266): 1.26e-100: 365: 38.12
+	Hs
		925201 RAC1_HUMAN (1-191): 1.75e-84: 249: 70.31		SPTB2_HUMAN (26-266): 1.26e-100: 365: 38.12
+	Hs
		893910 CDC42_HUMAN (1-191): 4.96e-82: 243: 100.00		SPTB2_HUMAN (26-266): 1.26e-100: 365: 38.12
+	Hs
		894227 CDC42_HUMAN (1-191): 4.96e-82: 243: 100.00		SYNE1_HUMAN (33-344): 6.35e-100: 364: 28.65
+	Hs
		950929 RHOG_HUMAN (1-191): 7.59e-82: 242: 60.73		SPTB2_HUMAN (26-266): 1.26e-100: 365: 38.12
+	Hs
		900386 RHOA_HUMAN (5-191): 3.88e-81: 240: 53.48		SPTB2_HUMAN (26-266): 1.26e-100: 365: 38.12
+	Hs
		545327 RAC2_HUMAN (1-191): 1.49e-80: 239: 68.75		SPTB2_HUMAN (26-266): 1.26e-100: 365: 38.12
+	Hs
		436258 RHOC_HUMAN (5-191): 3.64e-79: 235: 52.41		SPTB2_HUMAN (26-266): 1.26e-100: 365: 38.12
+	Hs
		892322 RAC3_HUMAN (1-177): 2.36e-78: 233: 72.32		SPTB2_HUMAN (26-266): 1.26e-100: 365: 38.12
+	Hs
		963356 RHOU_HUMAN (4-186): 1.03e-72: 221: 58.82		SPTB2_HUMAN (26-266): 1.26e-100: 365: 38.12
+	Hs
		363046 RAC1_HUMAN (1-191): 1.75e-84: 249: 70.31		FINC_HUMAN (1545-2724): 1.85e-65: 250: 13.83
+	Ce
		136793 RAC1_CAEEL (1-191): 5.53e-85: 250: 65.97		UNC89_CAEEL (406-2706): 4.03e-33: 144: 10.48
+	Ce
		104464 G5EBV3_CAEEL (2-191): 1e-81: 242: 58.95		UNC89_CAEEL (406-2706): 4.03e-33: 144: 10.48
+	Ce
		136794 CDC42_CAEEL (1-191): 1.83e-79: 236: 86.39		UNC89_CAEEL (406-2706): 4.03e-33: 144: 10.48