HitPredict

Interactor 1: CDC42 (P60953)
Cell division control protein 42 homolog (EC 3.6.5.2) (G25K GTP-binding protein)
Gene: CDC42

Interactor 2: ITSN1 (Q15811)
Intersectin-1 (SH3 domain-containing protein 1A) (SH3P17)
Gene: ITSN1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.70 1.00 0.838

The method score is based on:

Property Details
Experiments 11584276, 12006984
Identification Methods affinity chromatography technology, pull down, x-ray crystallography, enzymatic study
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains PH_13~Ras, Ras~RhoGEF
Common GO terms GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0008104 - protein localization
GO:0043005 - neuron projection
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 191
Hs

1 1721
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024