HitPredict

Interactor 1: CDC42 (P60953)
Cell division control protein 42 homolog (EC 3.6.5.2) (G25K GTP-binding protein)
Gene: CDC42

Interactor 2: RAB6D (Q53S08)
Ras-related protein Rab-6D (Rab6-like protein WTH3DI)
Gene: RAB6D

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Ras~Ras
Common GO terms	GO:0003924 - GTPase activity GO:0005525 - GTP binding GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 191 Hs			1 254
+	Hs
		564466 RHOQ_HUMAN (4-187): 7.35e-91: 266: 67.94		RAB8A_HUMAN (14-206): 7.15e-92: 271: 38.27
+	Hs
		564470 RHOQ_HUMAN (4-187): 7.35e-91: 266: 67.94		RAB1A_HUMAN (1-207): 8.4e-87: 258: 32.85
+	Hs
		894804 RHOJ_HUMAN (2-188): 2.67e-85: 252: 64.17		RAB8A_HUMAN (14-206): 7.15e-92: 271: 38.27
+	Hs
		894716 RAC1_HUMAN (1-191): 1.75e-84: 249: 70.31		RAB8A_HUMAN (14-206): 7.15e-92: 271: 38.27
+	Hs
		893847 CDC42_HUMAN (1-191): 4.96e-82: 243: 100.00		RAB8A_HUMAN (14-206): 7.15e-92: 271: 38.27
+	Hs
		894720 RHOG_HUMAN (1-191): 7.59e-82: 242: 60.73		RAB8A_HUMAN (14-206): 7.15e-92: 271: 38.27
+	Hs
		894710 RHOA_HUMAN (5-191): 3.88e-81: 240: 53.48		RAB8A_HUMAN (14-206): 7.15e-92: 271: 38.27
+	Hs
		918948 RHOJ_HUMAN (2-188): 2.67e-85: 252: 64.17		RAB1A_HUMAN (1-207): 8.4e-87: 258: 32.85
+	Hs
		918847 RAC1_HUMAN (1-191): 1.75e-84: 249: 70.31		RAB1A_HUMAN (1-207): 8.4e-87: 258: 32.85
+	Hs
		925600 RAC1_HUMAN (1-191): 1.75e-84: 249: 70.31		RAB1B_HUMAN (7-206): 7.04e-86: 255: 32.50
+	Hs
		893872 CDC42_HUMAN (1-191): 4.96e-82: 243: 100.00		RAB1A_HUMAN (1-207): 8.4e-87: 258: 32.85
+	Hs
		918849 RHOG_HUMAN (1-191): 7.59e-82: 242: 60.73		RAB1A_HUMAN (1-207): 8.4e-87: 258: 32.85
+	Hs
		894409 CDC42_HUMAN (1-191): 4.96e-82: 243: 100.00		RAB1B_HUMAN (7-206): 7.04e-86: 255: 32.50
+	Hs
		913995 RAC1_HUMAN (1-191): 1.75e-84: 249: 70.31		RB11A_HUMAN (3-209): 5.69e-82: 246: 27.78
+	Hs
		893868 CDC42_HUMAN (1-191): 4.96e-82: 243: 100.00		RB11A_HUMAN (3-209): 5.69e-82: 246: 27.78
+	Hs
		844737 RHOJ_HUMAN (2-188): 2.67e-85: 252: 64.17		RAB5C_HUMAN (8-178): 1.52e-45: 153: 42.69
+	Hs
		844473 RAC1_HUMAN (1-191): 1.75e-84: 249: 70.31		RAB5C_HUMAN (8-178): 1.52e-45: 153: 42.69
+	Hs
		844460 CDC42_HUMAN (1-191): 4.96e-82: 243: 100.00		RAB5C_HUMAN (8-178): 1.52e-45: 153: 42.69
+	Hs
		844464 RHOA_HUMAN (5-191): 3.88e-81: 240: 53.48		RAB5C_HUMAN (8-178): 1.52e-45: 153: 42.69
+	Hs
		893850 CDC42_HUMAN (1-191): 4.96e-82: 243: 100.00		RAB5B_HUMAN (13-203): 2.47e-43: 147: 40.10