HitPredict

Interactor 1: CDC42 (P60953)
Cell division control protein 42 homolog (EC 3.6.5.2) (G25K GTP-binding protein)
Gene: CDC42

Interactor 2: FLIP1 (Q7Z7B0)
Filamin-A-interacting protein 1 (FILIP)
Gene: FILIP1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.34	0.60	0.457

Property	Details
Experiments	21311754
Identification Methods	two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0098978 - glutamatergic synapse
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 191 Hs			1 1213
+	Hs
		725125 CDC42_HUMAN (1-191): 4.96e-82: 243: 100.00		MYH10_HUMAN (193-1014): 2.15e-38: 159: 12.08
+	Hs
		148653 RAC1_HUMAN (1-191): 1.75e-84: 249: 70.31		CTRO_HUMAN (20-666): 3.2e-30: 132: 11.57
+	Hs
		724757 RAC1_HUMAN (1-191): 1.75e-84: 249: 70.31		MYH9_HUMAN (367-991): 5.2e-25: 115: 11.61
+	Hs
		564758 RHOQ_HUMAN (4-187): 7.35e-91: 266: 67.94		MRCKB_HUMAN (1-411): 7.01e-17: 88.7: 11.22
+	Hs
		564571 RHOQ_HUMAN (4-187): 7.35e-91: 266: 67.94		MRCKG_HUMAN (2-276): 4.17e-15: 82.9: 10.49
+	Hs
		564564 RHOQ_HUMAN (4-187): 7.35e-91: 266: 67.94		MRCKA_HUMAN (1-382): 6.9e-13: 75.6: 10.47
+	Hs
		1331011 RHOJ_HUMAN (2-188): 2.67e-85: 252: 64.17		MRCKB_HUMAN (1-411): 7.01e-17: 88.7: 11.22
+	Hs
		925766 RAC1_HUMAN (1-191): 1.75e-84: 249: 70.31		MRCKB_HUMAN (1-411): 7.01e-17: 88.7: 11.22
+	Mm
		823530 RAC1_MOUSE (1-191): 1.75e-84: 249: 70.31		CTRO_MOUSE (15-536): 2.73e-16: 86.8: 14.18
+	Hs
		925356 RAC1_HUMAN (1-191): 1.75e-84: 249: 70.31		MRCKG_HUMAN (2-276): 4.17e-15: 82.9: 10.49
+	Hs
		564633 RHOQ_HUMAN (4-187): 7.35e-91: 266: 67.94		MY18A_HUMAN (181-697): 1.39e-09: 65.1: 18.38
+	Mm
		823529 CDC42_MOUSE (1-191): 4.96e-82: 243: 100.00		CTRO_MOUSE (15-536): 2.73e-16: 86.8: 14.18
+	Hs
		894047 CDC42_HUMAN (1-191): 4.96e-82: 243: 100.00		ITSN1_HUMAN (38-410): 9e-16: 85.3: 10.11
+	Hs
		1137905 RHOJ_HUMAN (2-188): 2.67e-85: 252: 64.17		MRCKA_HUMAN (1-382): 6.9e-13: 75.6: 10.47
+	Hs
		894128 CDC42_HUMAN (1-191): 4.96e-82: 243: 100.00		MRCKG_HUMAN (2-276): 4.17e-15: 82.9: 10.49
+	Hs
		925344 RAC1_HUMAN (1-191): 1.75e-84: 249: 70.31		MRCKA_HUMAN (1-382): 6.9e-13: 75.6: 10.47
+	Hs
		894116 CDC42_HUMAN (1-191): 4.96e-82: 243: 100.00		MRCKA_HUMAN (1-382): 6.9e-13: 75.6: 10.47
+	Hs
		925488 RAC1_HUMAN (1-191): 1.75e-84: 249: 70.31		MY18A_HUMAN (181-697): 1.39e-09: 65.1: 18.38
+	Hs
		551652 CDC42_HUMAN (1-191): 4.96e-82: 243: 100.00		DESP_HUMAN (129-749): 9.41e-10: 65.5: 20.64
+	Hs
		894274 CDC42_HUMAN (1-191): 4.96e-82: 243: 100.00		MY18A_HUMAN (181-697): 1.39e-09: 65.1: 18.38