HitPredict

Interactor 1: CDC42 (P60953)
Cell division control protein 42 homolog (EC 3.6.5.2) (G25K GTP-binding protein)
Gene: CDC42

Interactor 2: WIPF2 (Q8TF74)
WAS/WASL-interacting protein family member 2 (WASP-interacting protein-related protein) (WIP- and CR16-homologous protein) (WIP-related protein)
Gene: WIPF2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 191 Hs			1 440
+	Hs
		564611 RHOQ_HUMAN (4-187): 7.35e-91: 266: 67.94		MINK1_HUMAN (78-414): 1.1e-28: 121: 16.76
+	Hs
		1257319 RHOJ_HUMAN (2-188): 2.67e-85: 252: 64.17		WIPF2_HUMAN (1-440): 4.28e-32: 128: 100.00
+	Hs
		166043 RAC1_HUMAN (1-191): 1.75e-84: 249: 70.31		SYNJ2_HUMAN (6-410): 2.46e-30: 126: 12.59
+	Hs
		1233542 RHOJ_HUMAN (2-188): 2.67e-85: 252: 64.17		MINK1_HUMAN (78-414): 1.1e-28: 121: 16.76
+	Hs
		925434 RAC1_HUMAN (1-191): 1.75e-84: 249: 70.31		MINK1_HUMAN (78-414): 1.1e-28: 121: 16.76
+	Ce
		136793 RAC1_CAEEL (1-191): 5.53e-85: 250: 65.97		UNC89_CAEEL (97-369): 5.2e-27: 116: 13.29
+	Hs
		545493 RAC2_HUMAN (1-191): 1.49e-80: 239: 68.75		MINK1_HUMAN (78-414): 1.1e-28: 121: 16.76
+	Hs
		166039 RAC3_HUMAN (1-177): 2.36e-78: 233: 72.32		SYNJ2_HUMAN (6-410): 2.46e-30: 126: 12.59
+	Ce
		104464 G5EBV3_CAEEL (2-191): 1e-81: 242: 58.95		UNC89_CAEEL (97-369): 5.2e-27: 116: 13.29
+	Hs
		297840 RHOJ_HUMAN (2-188): 2.67e-85: 252: 64.17		K0754_HUMAN (1-345): 1.41e-23: 106: 11.18
+	Hs
		297823 RAC1_HUMAN (1-191): 1.75e-84: 249: 70.31		K0754_HUMAN (1-345): 1.41e-23: 106: 11.18
+	Ce
		136794 CDC42_CAEEL (1-191): 1.83e-79: 236: 86.39		UNC89_CAEEL (97-369): 5.2e-27: 116: 13.29
+	Hs
		297827 RHOG_HUMAN (1-191): 7.59e-82: 242: 60.73		K0754_HUMAN (1-345): 1.41e-23: 106: 11.18
+	Hs
		297820 RHOA_HUMAN (5-191): 3.88e-81: 240: 53.48		K0754_HUMAN (1-345): 1.41e-23: 106: 11.18
+	Hs
		297812 RAC2_HUMAN (1-191): 1.49e-80: 239: 68.75		K0754_HUMAN (1-345): 1.41e-23: 106: 11.18
+	Hs
		867087 CDC42_HUMAN (1-191): 4.96e-82: 243: 100.00		SC24C_HUMAN (62-332): 1.32e-22: 102: 19.32
+	Hs
		297809 RHOC_HUMAN (5-191): 3.64e-79: 235: 52.41		K0754_HUMAN (1-345): 1.41e-23: 106: 11.18
+	Hs
		62642 CDC42_HUMAN (1-191): 4.96e-82: 243: 100.00		WIPF3_HUMAN (24-435): 4.61e-21: 97.2: 29.33
+	Hs
		297819 RAC3_HUMAN (1-177): 2.36e-78: 233: 72.32		K0754_HUMAN (1-345): 1.41e-23: 106: 11.18
+	Hs
		900553 RHOA_HUMAN (5-191): 3.88e-81: 240: 53.48		TGO1_HUMAN (104-359): 3.95e-21: 98.8: 22.71