HitPredict

Interactor 1: CDC42 (P60953)
Cell division control protein 42 homolog (EC 3.6.5.2) (G25K GTP-binding protein)
Gene: CDC42

Interactor 2: DDRGK (Q96HY6)
DDRGK domain-containing protein 1 (Dashurin) (UFM1-binding and PCI domain-containing protein 1)
Gene: DDRGK1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005789 - endoplasmic reticulum membrane GO:0030335 - positive regulation of cell migration
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 191 Hs			1 314
+	Hs
		951234 RHOG_HUMAN (1-191): 7.59e-82: 242: 60.73		DDRGK_HUMAN (1-314): 5.29e-64: 206: 100.00
+	Hs
		900800 RHOA_HUMAN (5-191): 3.88e-81: 240: 53.48		DDRGK_HUMAN (1-314): 5.29e-64: 206: 100.00
+	Hs
		545559 RAC2_HUMAN (1-191): 1.49e-80: 239: 68.75		DDRGK_HUMAN (1-314): 5.29e-64: 206: 100.00
+	Hs
		436456 RHOC_HUMAN (5-191): 3.64e-79: 235: 52.41		DDRGK_HUMAN (1-314): 5.29e-64: 206: 100.00
+	Hs
		892537 RAC3_HUMAN (1-177): 2.36e-78: 233: 72.32		DDRGK_HUMAN (1-314): 5.29e-64: 206: 100.00
+	Sc
		580307 CDC42_YEAST (1-191): 2.69e-80: 238: 80.11		SEC3_YEAST (30-245): 1.63e-33: 132: 19.91