HitPredict

Interactor 1: CDC42 (P60953)
Cell division control protein 42 homolog (EC 3.6.5.2) (G25K GTP-binding protein)
Gene: CDC42

Interactor 2: RFIP5 (Q9BXF6)
Rab11 family-interacting protein 5 (Rab11-FIP5) (Gamma-SNAP-associated factor 1) (Gaf-1) (Phosphoprotein pp75) (Rab11-interacting protein Rip11)
Gene: RAB11FIP5

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	RBD-FIP~Ras
Common GO terms	GO:0000139 - Golgi membrane GO:0030141 - secretory granule GO:0045335 - phagocytic vesicle
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 191 Hs			1 653
+	Hs
		564668 RHOQ_HUMAN (4-187): 7.35e-91: 266: 67.94		RFIP5_HUMAN (1-653): 4.01e-162: 482: 100.00
+	Hs
		1315230 RHOJ_HUMAN (2-188): 2.67e-85: 252: 64.17		RFIP5_HUMAN (1-653): 4.01e-162: 482: 100.00
+	Hs
		925583 RAC1_HUMAN (1-191): 1.75e-84: 249: 70.31		RFIP5_HUMAN (1-653): 4.01e-162: 482: 100.00
+	Hs
		951290 RHOG_HUMAN (1-191): 7.59e-82: 242: 60.73		RFIP5_HUMAN (1-653): 4.01e-162: 482: 100.00
+	Hs
		545594 RAC2_HUMAN (1-191): 1.49e-80: 239: 68.75		RFIP5_HUMAN (1-653): 4.01e-162: 482: 100.00
+	Ce
		136793 RAC1_CAEEL (1-191): 5.53e-85: 250: 65.97		UNC89_CAEEL (164-653): 4.53e-35: 145: 9.40
+	Hs
		297840 RHOJ_HUMAN (2-188): 2.67e-85: 252: 64.17		K0754_HUMAN (146-604): 1.96e-33: 140: 9.61
+	Hs
		297823 RAC1_HUMAN (1-191): 1.75e-84: 249: 70.31		K0754_HUMAN (146-604): 1.96e-33: 140: 9.61
+	Ce
		104464 G5EBV3_CAEEL (2-191): 1e-81: 242: 58.95		UNC89_CAEEL (164-653): 4.53e-35: 145: 9.40
+	Hs
		297827 RHOG_HUMAN (1-191): 7.59e-82: 242: 60.73		K0754_HUMAN (146-604): 1.96e-33: 140: 9.61
+	Ce
		136794 CDC42_CAEEL (1-191): 1.83e-79: 236: 86.39		UNC89_CAEEL (164-653): 4.53e-35: 145: 9.40
+	Hs
		297820 RHOA_HUMAN (5-191): 3.88e-81: 240: 53.48		K0754_HUMAN (146-604): 1.96e-33: 140: 9.61
+	Hs
		297812 RAC2_HUMAN (1-191): 1.49e-80: 239: 68.75		K0754_HUMAN (146-604): 1.96e-33: 140: 9.61
+	Hs
		564580 RHOQ_HUMAN (4-187): 7.35e-91: 266: 67.94		RFIP1_HUMAN (405-650): 1.82e-10: 66.4: 21.14
+	Hs
		1167470 RHOJ_HUMAN (2-188): 2.67e-85: 252: 64.17		RFIP1_HUMAN (405-650): 1.82e-10: 66.4: 21.14
+	Hs
		925372 RAC1_HUMAN (1-191): 1.75e-84: 249: 70.31		RFIP1_HUMAN (405-650): 1.82e-10: 66.4: 21.14
+	Hs
		894148 CDC42_HUMAN (1-191): 4.96e-82: 243: 100.00		RFIP1_HUMAN (405-650): 1.82e-10: 66.4: 21.14
+	Hs
		951094 RHOG_HUMAN (1-191): 7.59e-82: 242: 60.73		RFIP1_HUMAN (405-650): 1.82e-10: 66.4: 21.14
+	Hs
		900608 RHOA_HUMAN (5-191): 3.88e-81: 240: 53.48		RFIP1_HUMAN (405-650): 1.82e-10: 66.4: 21.14
+	Hs
		545456 RAC2_HUMAN (1-191): 1.49e-80: 239: 68.75		RFIP1_HUMAN (405-650): 1.82e-10: 66.4: 21.14