HitPredict

Interactor 1: CDC42 (P60953)
Cell division control protein 42 homolog (EC 3.6.5.2) (G25K GTP-binding protein)
Gene: CDC42

Interactor 2: EHD4 (Q9H223)
EH domain-containing protein 4 (Hepatocellular carcinoma-associated protein 10/11) (PAST homolog 4)
Gene: EHD4

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	31478661
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005525 - GTP binding GO:0005737 - cytoplasm GO:0005886 - plasma membrane GO:0006897 - endocytosis GO:0016020 - membrane and 1 others more... GO:0070062 - extracellular exosome
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 191 Hs			1 541
+	Hs
		1328986 RHOJ_HUMAN (2-188): 2.67e-85: 252: 64.17		EHD4_HUMAN (1-541): 0: 839: 100.00
+	Hs
		564685 RHOQ_HUMAN (4-187): 7.35e-91: 266: 67.94		EHD1_HUMAN (1-535): 0: 823: 74.95
+	Hs
		925602 RAC1_HUMAN (1-191): 1.75e-84: 249: 70.31		EHD4_HUMAN (1-541): 0: 839: 100.00
+	Hs
		1330916 RHOJ_HUMAN (2-188): 2.67e-85: 252: 64.17		EHD1_HUMAN (1-535): 0: 823: 74.95
+	Hs
		564712 RHOQ_HUMAN (4-187): 7.35e-91: 266: 67.94		EHD2_HUMAN (1-535): 0: 799: 68.89
+	Hs
		545618 RAC2_HUMAN (1-191): 1.49e-80: 239: 68.75		EHD1_HUMAN (1-535): 0: 823: 74.95
+	Hs
		1183545 RHOU_HUMAN (4-186): 1.03e-72: 221: 58.82		EHD4_HUMAN (1-541): 0: 839: 100.00
+	Hs
		892597 RAC3_HUMAN (1-177): 2.36e-78: 233: 72.32		EHD1_HUMAN (1-535): 0: 823: 74.95
+	Hs
		1330957 RHOJ_HUMAN (2-188): 2.67e-85: 252: 64.17		EHD2_HUMAN (1-535): 0: 799: 68.89
+	Hs
		925677 RAC1_HUMAN (1-191): 1.75e-84: 249: 70.31		EHD2_HUMAN (1-535): 0: 799: 68.89
+	Hs
		894522 CDC42_HUMAN (1-191): 4.96e-82: 243: 100.00		EHD2_HUMAN (1-535): 0: 799: 68.89
+	Hs
		951410 RHOG_HUMAN (1-191): 7.59e-82: 242: 60.73		EHD2_HUMAN (1-535): 0: 799: 68.89
+	Hs
		900984 RHOA_HUMAN (5-191): 3.88e-81: 240: 53.48		EHD2_HUMAN (1-535): 0: 799: 68.89
+	Hs
		545664 RAC2_HUMAN (1-191): 1.49e-80: 239: 68.75		EHD2_HUMAN (1-535): 0: 799: 68.89
+	Hs
		436544 RHOC_HUMAN (5-191): 3.64e-79: 235: 52.41		EHD2_HUMAN (1-535): 0: 799: 68.89
+	Hs
		892636 RAC3_HUMAN (1-177): 2.36e-78: 233: 72.32		EHD2_HUMAN (1-535): 0: 799: 68.89
+	Hs
		894047 CDC42_HUMAN (1-191): 4.96e-82: 243: 100.00		ITSN1_HUMAN (428-540): 3.64e-30: 128: 36.28
+	Hs
		1078851 RHOU_HUMAN (4-186): 1.03e-72: 221: 58.82		ITSN1_HUMAN (428-540): 3.64e-30: 128: 36.28