HitPredict

Interactor 1: CDC42 (P60953)
Cell division control protein 42 homolog (EC 3.6.5.2) (G25K GTP-binding protein)
Gene: CDC42

Interactor 2: VTI1B (Q9UEU0)
Vesicle transport through interaction with t-SNAREs homolog 1B (Vesicle transport v-SNARE protein Vti1-like 1) (Vti1-rp1)
Gene: VTI1B

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005789 - endoplasmic reticulum membrane GO:0005829 - cytosol GO:0043025 - neuronal cell body
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 191 Hs			1 232
+	Hs
		564721 RHOQ_HUMAN (4-187): 7.35e-91: 266: 67.94		VTI1B_HUMAN (1-232): 7.05e-54: 174: 100.00
+	Hs
		1330970 RHOJ_HUMAN (2-188): 2.67e-85: 252: 64.17		VTI1B_HUMAN (1-232): 7.05e-54: 174: 100.00
+	Hs
		925701 RAC1_HUMAN (1-191): 1.75e-84: 249: 70.31		VTI1B_HUMAN (1-232): 7.05e-54: 174: 100.00
+	Hs
		951433 RHOG_HUMAN (1-191): 7.59e-82: 242: 60.73		VTI1B_HUMAN (1-232): 7.05e-54: 174: 100.00
+	Hs
		901014 RHOA_HUMAN (5-191): 3.88e-81: 240: 53.48		VTI1B_HUMAN (1-232): 7.05e-54: 174: 100.00
+	Hs
		545681 RAC2_HUMAN (1-191): 1.49e-80: 239: 68.75		VTI1B_HUMAN (1-232): 7.05e-54: 174: 100.00
+	Hs
		436450 RHOC_HUMAN (5-191): 3.64e-79: 235: 52.41		VTI1A_HUMAN (7-231): 7.83e-55: 176: 27.56
+	Hs
		436558 RHOC_HUMAN (5-191): 3.64e-79: 235: 52.41		VTI1B_HUMAN (1-232): 7.05e-54: 174: 100.00
+	Hs
		892658 RAC3_HUMAN (1-177): 2.36e-78: 233: 72.32		VTI1B_HUMAN (1-232): 7.05e-54: 174: 100.00
+	Hs
		151558 CDC42_HUMAN (1-191): 4.96e-82: 243: 100.00		GOSR2_HUMAN (11-226): 4.43e-45: 151: 15.07
+	Hs
		151563 RHOG_HUMAN (1-191): 7.59e-82: 242: 60.73		GOSR2_HUMAN (11-226): 4.43e-45: 151: 15.07
+	Hs
		151559 RHOA_HUMAN (5-191): 3.88e-81: 240: 53.48		GOSR2_HUMAN (11-226): 4.43e-45: 151: 15.07
+	Hs
		151545 RAC2_HUMAN (1-191): 1.49e-80: 239: 68.75		GOSR2_HUMAN (11-226): 4.43e-45: 151: 15.07
+	Hs
		151543 RHOC_HUMAN (5-191): 3.64e-79: 235: 52.41		GOSR2_HUMAN (11-226): 4.43e-45: 151: 15.07