Protein: GDIA
Rab GDP dissociation inhibitor alpha (Rab GDI alpha) (Guanosine diphosphate dissociation inhibitor 1) (GDI-1) (Oligophrenin-2) (Protein XAP-4)

Gene: GDIA, GDI1
Organism: Homo sapiens
Interactions: 122
UniProt ID: P31150

Gene Ontology (top 5):
GO:0005092 - GDP-dissociation inhibitor activity
GO:0005093 - Rab GDP-dissociation inhibitor activity
GO:0005096 - GTPase activator activity
GO:0005737 - cytoplasm
GO:0005783 - endoplasmic reticulum

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

724451

RAB9A
Ras-related protein Rab-9A

6

20

Small-scale

0.952

High

630702

RAB4A
Ras-related protein Rab-4A

6

20

Small-scale

0.950

High

724464

RAB1A
Ras-related protein Rab-1A

6

20

Small-scale

0.950

High

724456

RAB8A
Ras-related protein Rab-8A

6

20

Small-scale

0.949

High

724447

GDIB
Rab GDP dissociation inhibitor beta

6

1

High-throughput

0.947

High

724450

RAB7A
Ras-related protein Rab-7a

5

20

Small-scale

0.932

High

724452

RAB13
Ras-related protein Rab-13

5

20

Small-scale

0.932

High

724460

RAB10
Ras-related protein Rab-10

5

20

Small-scale

0.930

High

724488

RAB12
Ras-related protein Rab-12

5

20

Small-scale

0.930

High

724515

RAB1B
Ras-related protein Rab-1B

5

20

Small-scale

0.927

High

631084

RAB5A
Ras-related protein Rab-5A

5

20

High-throughput

0.925

High

631614

RAB6A
Ras-related protein Rab-6A

4

20

High-throughput

0.909

High

724461

RAB14
Ras-related protein Rab-14

4

20

High-throughput

0.909

High

724479

RAB35
Ras-related protein Rab-35

4

20

High-throughput

0.909

High

724505

RAB24
Ras-related protein Rab-24

4

20

High-throughput

0.909

High

724472

RAB31
Ras-related protein Rab-31

4

20

High-throughput

0.900

High

724523

RAB6B
Ras-related protein Rab-6B

4

20

High-throughput

0.900

High

630400

RAB3A
Ras-related protein Rab-3A

3

20

High-throughput

0.871

High

724463

RB11A
Ras-related protein Rab-11A

3

20

High-throughput

0.871

High

724528

RAB21
Ras-related protein Rab-21

3

20

High-throughput

0.871

High

724529

RB22A
Ras-related protein Rab-22A

3

20

High-throughput

0.871

High

724512

RAB34
Ras-related protein Rab-34

3

20

High-throughput

0.861

High

724518

RAB18
Ras-related protein Rab-18

3

20

High-throughput

0.861

High

724449

RAB5C
Ras-related protein Rab-5C

4

20

High-throughput

0.813

High

724459

RAB5B
Ras-related protein Rab-5B

4

20

High-throughput

0.813

High

724457

RAB4B
Ras-related protein Rab-4B

2

20

High-throughput

0.811

High

724458

RAB2A
Ras-related protein Rab-2A

2

20

High-throughput

0.811

High

724473

RAB32
Ras-related protein Rab-32

2

20

High-throughput

0.811

High

724493

RASEF
Ras and EF-hand domain-containing protein

2

20

High-throughput

0.811

High

724498

RAB2B
Ras-related protein Rab-2B

2

20

High-throughput

0.811

High

724502

RAB8B
Ras-related protein Rab-8B

3

20

High-throughput

0.779

High

724455

CDC42
Cell division control protein 42 homolog

1

1

Small-scale

0.724

High

724474

RB33A
Ras-related protein Rab-33A

1

20

High-throughput

0.691

High

724480

RB11B
Ras-related protein Rab-11B

1

20

High-throughput

0.691

High

724491

RAB43
Ras-related protein Rab-43

1

20

High-throughput

0.691

High

724514

RAB6C
Ras-related protein Rab-6C

1

20

High-throughput

0.691

High

724530

RAB23
Ras-related protein Rab-23

1

20

High-throughput

0.691

High

724527

UBP25
Ubiquitin carboxyl-terminal hydrolase 25

3

2

High-throughput

0.678

High

724497

LNX1
E3 ubiquitin-protein ligase LNX

2

2

High-throughput

0.654

High

630463

RAB3B
Ras-related protein Rab-3B

1

20

Small-scale

0.647

High

563277

CFTR
Cystic fibrosis transmembrane conductance regulator

2

1

High-throughput

0.601

High

240861

PRKN
E3 ubiquitin-protein ligase parkin

2

3

High-throughput

0.584

High

724485

Q5W0J0
RAB18, member RAS oncogene family

1

20

High-throughput

0.575

High

258776

DNJA2
DnaJ homolog subfamily A member 2

1

2

High-throughput

0.536

High

361135

SODC
Superoxide dismutase [Cu-Zn]

1

1

High-throughput

0.536

High

529180

TAU
Microtubule-associated protein tau

1

4

High-throughput

0.536

High

724448

EMD
Emerin

1

1

High-throughput

0.536

High

724469

HSP7E
Heat shock 70 kDa protein 14

1

3

High-throughput

0.536

High

724470

TIF1B
Transcription intermediary factor 1-beta

1

1

High-throughput

0.536

High

724471

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

1

High-throughput

0.536

High

724477

IQCB1
IQ calmodulin-binding motif-containing protein 1

1

1

High-throughput

0.536

High

724492

PLPL6
Patatin-like phospholipase domain-containing protein 6

1

1

High-throughput

0.536

High

724496

DYHC2
Cytoplasmic dynein 2 heavy chain 1

1

1

High-throughput

0.536

High

724503

CUL5
Cullin-5

1

1

High-throughput

0.536

High

724506

RNF31
E3 ubiquitin-protein ligase RNF31

1

1

High-throughput

0.536

High

724516

DNJC5
DnaJ homolog subfamily C member 5

1

2

High-throughput

0.536

High

724533

SAR1B
Small COPII coat GTPase SAR1B

1

15

High-throughput

0.536

High

105424

APRIO
Alternative prion protein

2

1

High-throughput

0.533

High

339061

NADK
NAD kinase

1

0

High-throughput

0.513

High

724462

PFD3
Prefoldin subunit 3

1

0

High-throughput

0.513

High

724467

TAP1
Antigen peptide transporter 1

1

0

High-throughput

0.513

High

724476

EXOS7
Exosome complex component RRP42

1

0

High-throughput

0.513

High

724495

FA98A
Protein FAM98A

1

0

High-throughput

0.513

High

724501

TANK
TRAF family member-associated NF-kappa-B activator

1

0

High-throughput

0.513

High

724507

FUBP3
Far upstream element-binding protein 3

1

0

High-throughput

0.513

High

724511

REPI1
DNA-binding protein REPIN1

1

0

High-throughput

0.513

High

724513

SHRPN
Sharpin

1

0

High-throughput

0.513

High

724524

INT13
Integrator complex subunit 13

1

0

High-throughput

0.513

High

724522

UBQL4
Ubiquilin-4

1

2

High-throughput

0.508

High

185457

OGT1
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit

1

4

High-throughput

0.501

High

227396

SPOP
Speckle-type POZ protein

1

0

High-throughput

0.493

High

175601

SR140
U2 snRNP-associated SURP motif-containing protein

1

1

High-throughput

0.489

High

405405

KITH
Thymidine kinase, cytosolic

1

0

High-throughput

0.486

High

724444

GNL1
Guanine nucleotide-binding protein-like 1

1

0

Small-scale

0.486

High

127285

LEG8
Galectin-8

1

1

Small-scale

0.479

High

315179

RECQ4
ATP-dependent DNA helicase Q4

1

1

High-throughput

0.479

High

403858

GCR
Glucocorticoid receptor

1

2

High-throughput

0.479

High

411438

NTRK1
High affinity nerve growth factor receptor

1

1

High-throughput

0.479

High

519777

ANDR
Androgen receptor

1

2

High-throughput

0.479

High

565790

EF2
Elongation factor 2

1

1

High-throughput

0.479

High

724445

MAP1B
Microtubule-associated protein 1B

1

2

High-throughput

0.479

High

724446

SOX2
Transcription factor SOX-2

1

1

High-throughput

0.479

High

724475

RBM39
RNA-binding protein 39

1

2

High-throughput

0.479

High

724478

ACAP2
Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 2

1

1

High-throughput

0.479

High

724489

TRI67
Tripartite motif-containing protein 67

1

6

High-throughput

0.479

High

724500

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

2

High-throughput

0.479

High

724509

ACON
Aconitate hydratase, mitochondrial

1

1

High-throughput

0.479

High

724510

BAG1
BAG family molecular chaperone regulator 1

1

1

High-throughput

0.479

High

724520

SIR7
NAD-dependent protein deacetylase sirtuin-7

1

1

High-throughput

0.479

High

724531

TRAK1
Trafficking kinesin-binding protein 1

1

1

High-throughput

0.479

High

379903

HLAB
HLA class I histocompatibility antigen, B alpha chain

1

0

High-throughput

0.458

High

417966

RPN2
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2

1

0

High-throughput

0.458

High

667574

CDK2
Cyclin-dependent kinase 2

1

0

High-throughput

0.458

High

724443

SOAT1
Sterol O-acyltransferase 1

1

0

High-throughput

0.458

High

724465

1433Z
14-3-3 protein zeta/delta

1

0

High-throughput

0.458

High

724468

TF65
Transcription factor p65

1

0

High-throughput

0.458

High

724487

VIR
Protein virilizer homolog

1

0

High-throughput

0.458

High

724490

FBX11
F-box only protein 11

1

0

High-throughput

0.458

High

724504

FBX32
F-box only protein 32

1

0

High-throughput

0.458

High

724519

ANLN
Anillin

1

0

High-throughput

0.458

High

724526

TRM7
tRNA

1

0

High-throughput

0.458

High

429374

JUN
Transcription factor Jun

1

2

High-throughput

0.445

High

724453

NCBP2
Nuclear cap-binding protein subunit 2

1

2

High-throughput

0.445

High

724454

TERA
Transitional endoplasmic reticulum ATPase

1

3

High-throughput

0.445

High

724482

NCBP3
Nuclear cap-binding protein subunit 3

1

1

High-throughput

0.445

High

724483

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

3

High-throughput

0.445

High

724508

SYGP1
Ras/Rap GTPase-activating protein SynGAP

1

1

High-throughput

0.445

High

724521

DISC1
Disrupted in schizophrenia 1 protein

1

0

High-throughput

0.438

High

588004

RFA2
Replication protein A 32 kDa subunit

1

2

High-throughput

0.437

High

694715

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

2

High-throughput

0.437

High

724442

RFA3
Replication protein A 14 kDa subunit

1

2

High-throughput

0.437

High

724481

EZH2
Histone-lysine N-methyltransferase EZH2

1

1

High-throughput

0.437

High

724494

GOLM1
Golgi membrane protein 1

1

0

Small-scale

0.426

High

724517

MLP3A
Microtubule-associated protein 1 light chain 3 alpha

1

0

High-throughput

0.426

High

724466

RUNX1
Runt-related transcription factor 1

1

0

High-throughput

0.282

High

724486

SPT2
Protein SPT2 homolog

1

0

High-throughput

0.279

Low

724499

HNRLL
Heterogeneous nuclear ribonucleoprotein L-like

1

0

High-throughput

0.279

Low

724525

BCD1
Box C/D snoRNA protein 1

1

0

High-throughput

0.279

Low

724532

TGRM1
TOG array regulator of axonemal microtubules protein 1

1

0

High-throughput

0.279

Low

702526

NDUS1
NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial

1

0

High-throughput

0.249

Low

724484

MIC10
MICOS complex subunit MIC10

1

0

Small-scale

0.249

Low

515751

NARR
Ras-related protein Rab-34, isoform NARR

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025