HitPredict

Interactor 1: CDC42 (P60953)
Cell division control protein 42 homolog (EC 3.6.5.2) (G25K GTP-binding protein)
Gene: CDC42

Interactor 2: LIMA1 (Q9UHB6)
LIM domain and actin-binding protein 1 (Epithelial protein lost in neoplasm)
Gene: LIMA1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.70	0.60	0.650

Property	Details
Experiments	26496610, 31980649, unassigned2173
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0005925 - focal adhesion
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 191 Hs			1 759
+	Hs
		925707 RAC1_HUMAN (1-191): 1.75e-84: 249: 70.31		LIMA1_HUMAN (1-759): 0: 855: 100.00
+	Hs
		901022 RHOA_HUMAN (5-191): 3.88e-81: 240: 53.48		LIMA1_HUMAN (1-759): 0: 855: 100.00
+	Hs
		564587 RHOQ_HUMAN (4-187): 7.35e-91: 266: 67.94		MICA3_HUMAN (271-544): 5.7e-43: 170: 23.93
+	Hs
		1186089 RHOJ_HUMAN (2-188): 2.67e-85: 252: 64.17		MICA3_HUMAN (271-544): 5.7e-43: 170: 23.93
+	Hs
		925387 RAC1_HUMAN (1-191): 1.75e-84: 249: 70.31		MICA3_HUMAN (271-544): 5.7e-43: 170: 23.93
+	Hs
		892450 RAC3_HUMAN (1-177): 2.36e-78: 233: 72.32		MICA3_HUMAN (271-544): 5.7e-43: 170: 23.93
+	Hs
		564610 RHOQ_HUMAN (4-187): 7.35e-91: 266: 67.94		MILK1_HUMAN (355-540): 3.05e-31: 133: 21.81
+	Hs
		1232332 RHOJ_HUMAN (2-188): 2.67e-85: 252: 64.17		MILK1_HUMAN (355-540): 3.05e-31: 133: 21.81
+	Hs
		925433 RAC1_HUMAN (1-191): 1.75e-84: 249: 70.31		MILK1_HUMAN (355-540): 3.05e-31: 133: 21.81
+	Hs
		894206 CDC42_HUMAN (1-191): 4.96e-82: 243: 100.00		MILK1_HUMAN (355-540): 3.05e-31: 133: 21.81
+	Hs
		951148 RHOG_HUMAN (1-191): 7.59e-82: 242: 60.73		MILK1_HUMAN (355-540): 3.05e-31: 133: 21.81
+	Hs
		900682 RHOA_HUMAN (5-191): 3.88e-81: 240: 53.48		MILK1_HUMAN (355-540): 3.05e-31: 133: 21.81
+	Hs
		892482 RAC3_HUMAN (1-177): 2.36e-78: 233: 72.32		MILK1_HUMAN (355-540): 3.05e-31: 133: 21.81
+	Hs
		857915 CDC42_HUMAN (1-191): 4.96e-82: 243: 100.00		CRIP2_HUMAN (348-471): 3.86e-29: 117: 27.48
+	Hs
		1183462 RHOU_HUMAN (4-186): 1.03e-72: 221: 58.82		MILK1_HUMAN (355-540): 3.05e-31: 133: 21.81
+	Dd
		246627 RAC1A_DICDI (1-191): 6.92e-83: 245: 65.46		LIME_DICDI (386-441): 1.2e-21: 95.3: 42.86
+	Gg
		823526 Q6LC82_CHICK (1-191): 1.75e-84: 249: 70.31		PAXI_CHICK (268-446): 3.73e-14: 78.1: 14.53
+	Hs
		823429 RHOU_HUMAN (4-186): 1.03e-72: 221: 58.82		PAXI_HUMAN (268-446): 5.9e-14: 77.3: 14.53