Protein: GDIB
Rab GDP dissociation inhibitor beta (Rab GDI beta) (Guanosine diphosphate dissociation inhibitor 2) (GDI-2)

Gene: GDIB, GDI2
Organism: Homo sapiens
Interactions: 170
UniProt ID: P50395

Gene Ontology (top 5):
GO:0003723 - RNA binding
GO:0005093 - Rab GDP-dissociation inhibitor activity
GO:0005096 - GTPase activator activity
GO:0005576 - extracellular region
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

631123

RAB5A
Ras-related protein Rab-5A

7

20

Small-scale

0.963

High

894510

RAB9A
Ras-related protein Rab-9A

6

20

Small-scale

0.948

High

724447

GDIA
Rab GDP dissociation inhibitor alpha

6

1

High-throughput

0.947

High

630724

RAB4A
Ras-related protein Rab-4A

6

20

Small-scale

0.944

High

894521

RAB8A
Ras-related protein Rab-8A

5

20

Small-scale

0.919

High

894508

RAB5C
Ras-related protein Rab-5C

4

20

High-throughput

0.903

High

894530

RAB1A
Ras-related protein Rab-1A

4

20

Small-scale

0.903

High

894582

RAB24
Ras-related protein Rab-24

4

20

High-throughput

0.903

High

894591

RAB1B
Ras-related protein Rab-1B

4

20

High-throughput

0.903

High

894541

RAB31
Ras-related protein Rab-31

4

20

High-throughput

0.892

High

630409

RAB3A
Ras-related protein Rab-3A

3

20

High-throughput

0.871

High

894600

RAB6B
Ras-related protein Rab-6B

3

20

High-throughput

0.871

High

894522

RAB2A
Ras-related protein Rab-2A

3

20

Small-scale

0.853

High

894529

RB11A
Ras-related protein Rab-11A

3

20

Small-scale

0.853

High

894509

RAB7A
Ras-related protein Rab-7a

3

20

Small-scale

0.847

High

894580

RAB8B
Ras-related protein Rab-8B

2

20

High-throughput

0.811

High

894606

RAB21
Ras-related protein Rab-21

2

20

High-throughput

0.811

High

894576

RAB2B
Ras-related protein Rab-2B

2

20

High-throughput

0.802

High

894551

RAB35
Ras-related protein Rab-35

2

20

High-throughput

0.789

High

894524

RAB10
Ras-related protein Rab-10

2

20

Small-scale

0.776

High

894558

RAB12
Ras-related protein Rab-12

2

20

Small-scale

0.776

High

631626

RAB6A
Ras-related protein Rab-6A

1

20

High-throughput

0.691

High

894511

RAB13
Ras-related protein Rab-13

1

20

High-throughput

0.691

High

894523

RAB5B
Ras-related protein Rab-5B

1

20

High-throughput

0.691

High

894526

RAB14
Ras-related protein Rab-14

1

20

High-throughput

0.691

High

894542

RAB32
Ras-related protein Rab-32

1

20

High-throughput

0.691

High

894544

RB33A
Ras-related protein Rab-33A

1

20

High-throughput

0.691

High

894553

RB11B
Ras-related protein Rab-11B

1

20

High-throughput

0.691

High

894565

RAB43
Ras-related protein Rab-43

1

20

High-throughput

0.691

High

894598

RAB18
Ras-related protein Rab-18

1

20

High-throughput

0.691

High

894607

RB22A
Ras-related protein Rab-22A

1

20

High-throughput

0.691

High

894608

RAB23
Ras-related protein Rab-23

1

20

High-throughput

0.691

High

389160

FINC
Fibronectin

3

0

High-throughput

0.646

High

894519

RAB25
Ras-related protein Rab-25

1

20

High-throughput

0.618

High

894595

PAAT
ATPase PAAT

2

0

High-throughput

0.602

High

241106

PRKN
E3 ubiquitin-protein ligase parkin

2

3

High-throughput

0.584

High

717267

PEBP1
Phosphatidylethanolamine-binding protein 1

2

1

High-throughput

0.571

High

894532

KPCE
Protein kinase C epsilon type

2

1

High-throughput

0.571

High

226729

SGTA
Small glutamine-rich tetratricopeptide repeat-containing protein alpha

1

6

High-throughput

0.536

High

277603

H2AY
Core histone macro-H2A.1

1

1

High-throughput

0.536

High

317993

TOM70
Mitochondrial import receptor subunit TOM70

1

5

High-throughput

0.536

High

529356

TAU
Microtubule-associated protein tau

1

4

High-throughput

0.536

High

563432

CFTR
Cystic fibrosis transmembrane conductance regulator

1

1

High-throughput

0.536

High

679102

DNJB1
DnaJ homolog subfamily B member 1

1

3

High-throughput

0.536

High

761348

HS71L
Heat shock 70 kDa protein 1-like

1

2

High-throughput

0.536

High

783535

MP2K2
Dual specificity mitogen-activated protein kinase kinase 2

1

2

High-throughput

0.536

High

894535

KPCZ
Protein kinase C zeta type

1

2

High-throughput

0.536

High

894549

IQCB1
IQ calmodulin-binding motif-containing protein 1

1

1

High-throughput

0.536

High

894550

IF4H
Eukaryotic translation initiation factor 4H

1

3

High-throughput

0.536

High

894575

NEK7
Serine/threonine-protein kinase Nek7

1

1

High-throughput

0.536

High

894588

KPCD2
Serine/threonine-protein kinase D2

1

5

High-throughput

0.536

High

894603

DNJB4
DnaJ homolog subfamily B member 4

1

3

High-throughput

0.536

High

894615

SAR1B
Small COPII coat GTPase SAR1B

1

15

High-throughput

0.536

High

415432

HSPB1
Heat shock protein beta-1

1

0

High-throughput

0.518

High

66487

RASFA
Ras association domain-containing protein 10

1

0

High-throughput

0.513

High

213864

M3K7
Mitogen-activated protein kinase kinase kinase 7

1

0

High-throughput

0.513

High

298327

DNJC8
DnaJ homolog subfamily C member 8

1

0

High-throughput

0.513

High

385564

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

0

High-throughput

0.513

High

762111

CNR2
Cannabinoid receptor 2

1

0

Small-scale

0.513

High

894537

CSN1
COP9 signalosome complex subunit 1

1

0

High-throughput

0.513

High

894548

RRS1
Ribosome biogenesis regulatory protein homolog

1

0

High-throughput

0.513

High

894552

MYLK
Myosin light chain kinase, smooth muscle

1

0

High-throughput

0.513

High

894567

SKA3
Spindle and kinetochore-associated protein 3

1

0

High-throughput

0.513

High

185529

OGT1
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit

1

4

High-throughput

0.501

High

353110

AGR2
Anterior gradient protein 2 homolog

1

0

High-throughput

0.493

High

122935

SGK1
Serine/threonine-protein kinase Sgk1

1

2

High-throughput

0.479

High

125320

LEG9
Galectin-9

1

1

High-throughput

0.479

High

315292

RECQ4
ATP-dependent DNA helicase Q4

1

1

High-throughput

0.479

High

362018

AATM
Aspartate aminotransferase, mitochondrial

1

1

High-throughput

0.479

High

425380

ISG15
Ubiquitin-like protein ISG15

1

4

High-throughput

0.479

High

536762

HSP7C
Heat shock cognate 71 kDa protein

1

2

High-throughput

0.479

High

606439

CEBPB
CCAAT/enhancer-binding protein beta

1

1

High-throughput

0.479

High

623197

RO52
E3 ubiquitin-protein ligase TRIM21

1

1

High-throughput

0.479

High

685455

U2AF2
Splicing factor U2AF 65 kDa subunit

1

4

High-throughput

0.479

High

774209

BASI
Basigin

1

2

High-throughput

0.479

High

861065

MAP1B
Microtubule-associated protein 1B

1

2

High-throughput

0.479

High

872080

SOX2
Transcription factor SOX-2

1

1

High-throughput

0.479

High

894512

BAP31
B-cell receptor-associated protein 31

1

1

Small-scale

0.479

High

894520

ACTB
Actin, cytoplasmic 1

1

1

High-throughput

0.479

High

894525

UBC12
NEDD8-conjugating enzyme Ubc12

1

2

High-throughput

0.479

High

894527

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

3

High-throughput

0.479

High

894528

ARF6
ADP-ribosylation factor 6

1

13

High-throughput

0.479

High

894533

AKA12
A-kinase anchor protein 12

1

3

High-throughput

0.479

High

894536

MERTK
Tyrosine-protein kinase Mer

1

1

High-throughput

0.479

High

894540

CUL3
Cullin-3

1

1

High-throughput

0.479

High

894545

TRI25
E3 ubiquitin/ISG15 ligase TRIM25

1

2

High-throughput

0.479

High

894546

RBM39
RNA-binding protein 39

1

2

High-throughput

0.479

High

894547

EMC2
ER membrane protein complex subunit 2

1

2

High-throughput

0.479

High

894554

EZH2
Histone-lysine N-methyltransferase EZH2

1

1

High-throughput

0.479

High

894561

TRI67
Tripartite motif-containing protein 67

1

6

High-throughput

0.479

High

894564

HUWE1
E3 ubiquitin-protein ligase HUWE1

1

2

High-throughput

0.479

High

894577

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

2

High-throughput

0.479

High

894578

HS105
Heat shock protein 105 kDa

1

5

High-throughput

0.479

High

894579

AKAP1
A-kinase anchor protein 1, mitochondrial

1

1

High-throughput

0.479

High

894584

CHM4C
Charged multivesicular body protein 4c

1

2

High-throughput

0.479

High

894586

NECD
Necdin

1

1

High-throughput

0.479

High

894587

BAG1
BAG family molecular chaperone regulator 1

1

1

High-throughput

0.479

High

894590

ARP6
Actin-related protein 6

1

2

High-throughput

0.479

High

894594

PKHA4
Pleckstrin homology domain-containing family A member 4

1

1

High-throughput

0.479

High

894596

SMUF1
E3 ubiquitin-protein ligase SMURF1

1

2

High-throughput

0.479

High

894597

TRI39
E3 ubiquitin-protein ligase TRIM39

1

1

Small-scale

0.479

High

894599

SIR7
NAD-dependent protein deacetylase sirtuin-7

1

1

High-throughput

0.479

High

894602

ZO2
Tight junction protein 2

1

4

High-throughput

0.479

High

894605

ZRAN1
Ubiquitin thioesterase ZRANB1

1

1

High-throughput

0.479

High

894610

TRAK1
Trafficking kinesin-binding protein 1

1

1

High-throughput

0.479

High

894614

TRAF6
TNF receptor-associated factor 6

1

4

High-throughput

0.479

High

254560

EIF1B
Eukaryotic translation initiation factor 1b

1

0

High-throughput

0.458

High

319531

UFL1
E3 UFM1-protein ligase 1

1

0

High-throughput

0.458

High

332088

MRP6
ATP-binding cassette sub-family C member 6

1

0

Small-scale

0.458

High

347580

BAG3
BAG family molecular chaperone regulator 3

1

0

High-throughput

0.458

High

377192

SOMA
Somatotropin

1

0

High-throughput

0.458

High

420429

AT1A1
Sodium/potassium-transporting ATPase subunit alpha-1

1

0

High-throughput

0.458

High

457309

TBB5
Tubulin beta chain

1

0

High-throughput

0.458

High

487095

PARP1
Poly [ADP-ribose] polymerase 1

1

0

High-throughput

0.458

High

557955

XRCC6
X-ray repair cross-complementing protein 6

1

0

High-throughput

0.458

High

822536

VHL
von Hippel-Lindau disease tumor suppressor

1

0

High-throughput

0.458

High

830353

CCNF
Cyclin-F

1

0

High-throughput

0.458

High

887842

MCM2
DNA replication licensing factor MCM2

1

0

High-throughput

0.458

High

894507

PPT1
Palmitoyl-protein thioesterase 1

1

0

High-throughput

0.458

High

894515

IF6
Eukaryotic translation initiation factor 6

1

0

High-throughput

0.458

High

894538

PAK2
Serine/threonine-protein kinase PAK 2

1

0

High-throughput

0.458

High

894539

BIRC3
Baculoviral IAP repeat-containing protein 3

1

0

High-throughput

0.458

High

894543

APR
Phorbol-12-myristate-13-acetate-induced protein 1

1

0

High-throughput

0.458

High

894555

NREP
Neuronal regeneration-related protein

1

0

Small-scale

0.458

High

894569

FA20C
Extracellular serine/threonine protein kinase FAM20C

1

0

High-throughput

0.458

High

894570

EMC5
ER membrane protein complex subunit 5

1

0

High-throughput

0.458

High

894571

EMC1
ER membrane protein complex subunit 1

1

0

High-throughput

0.458

High

894572

NHLC2
NHL repeat-containing protein 2

1

0

High-throughput

0.458

High

894573

RN149
E3 ubiquitin-protein ligase RNF149

1

0

High-throughput

0.458

High

894574

BICD2
Protein bicaudal D homolog 2

1

0

High-throughput

0.458

High

894583

VP33A
Vacuolar protein sorting-associated protein 33A

1

0

High-throughput

0.458

High

894585

CI072
Guanine nucleotide exchange factor C9orf72

1

0

High-throughput

0.458

High

894592

ATG5
Autophagy protein 5

1

0

High-throughput

0.458

High

894601

PD1L1
Programmed cell death 1 ligand 1

1

0

High-throughput

0.458

High

894609

FZR1
Fizzy-related protein homolog

1

0

High-throughput

0.458

High

894611

AAKB1
5'-AMP-activated protein kinase subunit beta-1

1

0

High-throughput

0.458

High

894612

TRRAP
Transformation/transcription domain-associated protein

1

0

High-throughput

0.458

High

894613

LOXL2
Lysyl oxidase homolog 2

1

0

High-throughput

0.458

High

184607

MK13
Mitogen-activated protein kinase 13

1

1

Small-scale

0.445

High

429535

JUN
Transcription factor Jun

1

2

High-throughput

0.445

High

894513

NCBP2
Nuclear cap-binding protein subunit 2

1

2

High-throughput

0.445

High

894514

TERA
Transitional endoplasmic reticulum ATPase

1

3

High-throughput

0.445

High

894517

RIPK4
Receptor-interacting serine/threonine-protein kinase 4

1

1

High-throughput

0.445

High

894531

TAGL
Transgelin

1

1

High-throughput

0.445

High

894556

NCBP3
Nuclear cap-binding protein subunit 3

1

1

High-throughput

0.445

High

894559

PKHA7
Pleckstrin homology domain-containing family A member 7

1

2

High-throughput

0.445

High

894562

NEK10
Serine/threonine-protein kinase Nek10

1

2

High-throughput

0.445

High

105585

APRIO
Alternative prion protein

1

1

High-throughput

0.437

High

142897

NFIB
Nuclear factor 1 B-type

1

1

High-throughput

0.437

High

473859

NFIC
Nuclear factor 1 C-type

1

1

High-throughput

0.437

High

588215

RFA2
Replication protein A 32 kDa subunit

1

2

High-throughput

0.437

High

694941

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

2

High-throughput

0.437

High

767710

RFA3
Replication protein A 14 kDa subunit

1

2

High-throughput

0.437

High

894563

ASXL2
Putative Polycomb group protein ASXL2

1

4

High-throughput

0.437

High

894568

ASXL1
Polycomb group protein ASXL1

1

2

High-throughput

0.437

High

894589

ASXL3
Putative Polycomb group protein ASXL3

1

5

High-throughput

0.437

High

894593

Q9H4D1
Receptor-interacting serine/threonine-protein kinase 4

1

1

High-throughput

0.437

High

894604

EPHA6
Ephrin type-A receptor 6

1

1

High-throughput

0.437

High

894516

BACE1
Beta-secretase 1

1

0

Small-scale

0.426

High

894518

NAC3
Sodium/calcium exchanger 3

1

0

High-throughput

0.426

High

894557

Q5TBM3
Heat shock protein family H

1

2

High-throughput

0.407

High

886640

CEBPA
CCAAT/enhancer-binding protein alpha

1

1

High-throughput

0.373

High

658516

GLRA2
Glycine receptor subunit alpha-2

1

0

High-throughput

0.282

High

124272

HAX1
HCLS1-associated protein X-1

1

0

High-throughput

0.249

Low

239773

PCDH7
Protocadherin-7

1

0

High-throughput

0.249

Low

259636

BRD4
Bromodomain-containing protein 4

1

0

High-throughput

0.249

Low

894581

TNR14
Tumor necrosis factor receptor superfamily member 14

1

0

High-throughput

0.249

Low

894534

P
P protein

1

0

High-throughput

0.232

Low

894560

TIFAB
TRAF-interacting protein with FHA domain-containing protein B

1

0

High-throughput

0.232

Low

894566

S41A1
Solute carrier family 41 member 1

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025