HitPredict

Interactor 1: CDC42 (P60953)
Cell division control protein 42 homolog (EC 3.6.5.2) (G25K GTP-binding protein)
Gene: CDC42

Interactor 2: LTOR2 (Q9Y2Q5)
Ragulator complex protein LAMTOR2 (Endosomal adaptor protein p14) (Late endosomal/lysosomal Mp1-interacting protein) (Late endosomal/lysosomal adaptor and MAPK and MTOR activator 2) (Mitogen-activated protein-binding protein-interacting protein) (MAPBP-interacting protein) (Roadblock domain-containing protein 3)
Gene: LAMTOR2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0008104 - protein localization
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 191 Hs			1 125
+	Hs
		564750 RHOQ_HUMAN (4-187): 7.35e-91: 266: 67.94		LTOR2_HUMAN (1-125): 1.93e-61: 185: 100.00
+	Hs
		951472 RHOG_HUMAN (1-191): 7.59e-82: 242: 60.73		LTOR2_HUMAN (1-125): 1.93e-61: 185: 100.00
+	Hs
		901067 RHOA_HUMAN (5-191): 3.88e-81: 240: 53.48		LTOR2_HUMAN (1-125): 1.93e-61: 185: 100.00
+	Hs
		545707 RAC2_HUMAN (1-191): 1.49e-80: 239: 68.75		LTOR2_HUMAN (1-125): 1.93e-61: 185: 100.00
+	Hs
		436579 RHOC_HUMAN (5-191): 3.64e-79: 235: 52.41		LTOR2_HUMAN (1-125): 1.93e-61: 185: 100.00