HitPredict

Interactor 1: RAB8A (P61006)
Ras-related protein Rab-8A (EC 3.6.5.2) (Oncogene c-mel)
Gene: RAB8A

Interactor 2: TBC15 (Q8TC07)
TBC1 domain family member 15 (GTPase-activating protein RAB7) (GAP for RAB7) (Rab7-GAP)
Gene: TBC1D15

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.80	0.514

Property	Details
Experiments	26824392
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	PH_RBD~Ras, RabGAP-TBC~Ras
Common GO terms	-
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 207 Hs			1 691
+	Hs
		918951 RAB1A_HUMAN (1-204): 1.23e-87: 258: 54.41		TBC17_HUMAN (1-644): 1.78e-176: 519: 47.45
+	Hs
		894809 RAB8A_HUMAN (1-207): 1.67e-86: 255: 100.00		TBC17_HUMAN (1-644): 1.78e-176: 519: 47.45
+	Os
		1130874 Q7XHP7_ORYSJ (4-204): 3.33e-96: 280: 61.39		Q5SMT0_ORYSJ (11-641): 2.37e-147: 446: 30.74
+	Os
		772871 RIC2_ORYSJ (4-205): 1.14e-80: 241: 41.06		Q5SMT0_ORYSJ (11-641): 2.37e-147: 446: 30.74
+	Os
		1130875 Q84TA8_ORYSJ (4-204): 1.28e-80: 240: 60.89		Q5SMT0_ORYSJ (11-641): 2.37e-147: 446: 30.74
+	Hs
		895536 RAB10_HUMAN (3-181): 4.07e-93: 272: 75.98		EVI5L_HUMAN (233-676): 1.48e-82: 279: 14.00
+	Hs
		1079952 RB11B_HUMAN (4-204): 1.1e-88: 261: 41.63		EVI5L_HUMAN (233-676): 1.48e-82: 279: 14.00
+	Hs
		1079972 RB11B_HUMAN (4-204): 1.1e-88: 261: 41.63		TBC14_HUMAN (207-642): 1.52e-83: 279: 14.55
+	Hs
		894727 RAB8A_HUMAN (1-207): 1.67e-86: 255: 100.00		TBC8B_HUMAN (160-667): 4.89e-82: 283: 13.67
+	Hs
		894747 RAB8A_HUMAN (1-207): 1.67e-86: 255: 100.00		TBC9B_HUMAN (196-671): 5.6e-80: 279: 14.85
+	Hs
		914391 RB11A_HUMAN (4-204): 5.02e-81: 242: 41.06		TB22B_HUMAN (157-625): 1.72e-89: 290: 18.68
+	Hs
		234378 RB11B_HUMAN (4-204): 1.1e-88: 261: 41.63		EVI5_HUMAN (272-636): 2.43e-75: 260: 16.17
+	Hs
		914275 RB11A_HUMAN (4-204): 5.02e-81: 242: 41.06		EVI5L_HUMAN (233-676): 1.48e-82: 279: 14.00
+	Hs
		914423 RB11A_HUMAN (4-204): 5.02e-81: 242: 41.06		TBC14_HUMAN (207-642): 1.52e-83: 279: 14.55
+	Hs
		233036 RB11A_HUMAN (4-204): 5.02e-81: 242: 41.06		TBC12_HUMAN (208-642): 9.47e-82: 277: 14.55
+	Hs
		321281 RB11A_HUMAN (4-204): 5.02e-81: 242: 41.06		TBCD8_HUMAN (173-660): 1.44e-79: 276: 13.21
+	Hs
		914176 RB11A_HUMAN (4-204): 5.02e-81: 242: 41.06		TBCD1_HUMAN (198-649): 1.54e-76: 268: 17.92
+	Sc
		350927 YPT1_YEAST (1-204): 6.16e-81: 241: 49.03		GYP1_YEAST (285-557): 1.13e-79: 268: 22.85
+	Hs
		234370 RB11A_HUMAN (4-204): 5.02e-81: 242: 41.06		EVI5_HUMAN (272-636): 2.43e-75: 260: 16.17