HitPredict

Interactor 1: RAB10 (P61026)
Ras-related protein Rab-10 (EC 3.6.5.2)
Gene: RAB10

Interactor 2: RIPL1 (Q5EBL4)
RILP-like protein 1 (Rab-interacting lysosomal-like protein 1)
Gene: RILPL1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.64	1.00	0.805

Property	Details
Experiments	30398148, 26824392, 29125462
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	RILP~Ras
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0005929 - cilium
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 200 Hs			1 403
+	Hs
		894744 RAB8A_HUMAN (1-199): 1.02e-96: 281: 67.32		RIPL1_HUMAN (1-403): 6.12e-105: 317: 100.00
+	Mm
		877204 RAB8A_MOUSE (4-181): 5.12e-93: 271: 75.98		RIPL1_MOUSE (1-403): 9.92e-107: 322: 92.86
+	Hs
		914109 RB11A_HUMAN (3-200): 6.11e-83: 246: 40.19		RIPL1_HUMAN (1-403): 6.12e-105: 317: 100.00
+	Hs
		894827 RAB8A_HUMAN (1-199): 1.02e-96: 281: 67.32		JIP3_HUMAN (20-318): 5.16e-78: 264: 16.83
+	Hs
		229651 RAB8A_HUMAN (1-199): 1.02e-96: 281: 67.32		JIP4_HUMAN (20-288): 4.85e-74: 252: 16.91
+	Hs
		895567 RAB10_HUMAN (1-200): 3.02e-89: 262: 100.00		JIP3_HUMAN (20-318): 5.16e-78: 264: 16.83
+	Hs
		229652 RAB10_HUMAN (1-200): 3.02e-89: 262: 100.00		JIP4_HUMAN (20-288): 4.85e-74: 252: 16.91
+	Hs
		894788 RAB8A_HUMAN (1-199): 1.02e-96: 281: 67.32		RIPL2_HUMAN (229-365): 3.35e-24: 101: 34.72
+	Mm
		877201 RAB8A_MOUSE (4-181): 5.12e-93: 271: 75.98		RIPL2_MOUSE (229-361): 2.55e-25: 103: 34.31
+	Hs
		895533 RAB10_HUMAN (1-200): 3.02e-89: 262: 100.00		RIPL2_HUMAN (229-365): 3.35e-24: 101: 34.72