HitPredict

Interactor 1: RAB10 (P61026)
Ras-related protein Rab-10 (EC 3.6.5.2)
Gene: RAB10

Interactor 2: RAB6C (Q9H0N0)
Ras-related protein Rab-6C (Rab6-like protein WTH3)
Gene: RAB6C

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	26824392
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	Ras~Ras
Common GO terms	GO:0005525 - GTP binding GO:0005794 - Golgi apparatus GO:0005829 - cytosol
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 200 Hs			1 254
+	Hs
		894803 RAB8A_HUMAN (1-199): 1.02e-96: 281: 67.32		RAB6C_HUMAN (1-254): 4.39e-105: 306: 100.00
+	Mm
		877189 RAB8B_MOUSE (1-198): 3.07e-100: 290: 70.20		RAB8A_MOUSE (14-207): 3.64e-92: 272: 38.07
+	Hs
		894787 RAB8B_HUMAN (1-198): 2.21e-100: 290: 70.20		RAB8A_HUMAN (14-206): 6.02e-92: 271: 37.76
+	Hs
		1273009 RAB8B_HUMAN (1-198): 2.21e-100: 290: 70.20		RAB1B_HUMAN (7-206): 6.49e-84: 250: 32.00
+	Mm
		877188 RAB10_MOUSE (1-200): 3.02e-89: 262: 100.00		RAB8A_MOUSE (14-207): 3.64e-92: 272: 38.07
+	Hs
		894715 RAB8A_HUMAN (1-199): 1.02e-96: 281: 67.32		RAB1A_HUMAN (1-207): 5.76e-85: 253: 32.37
+	Hs
		894709 RAB10_HUMAN (1-200): 3.02e-89: 262: 100.00		RAB8A_HUMAN (14-206): 6.02e-92: 271: 37.76
+	Hs
		592647 RAB8A_HUMAN (1-199): 1.02e-96: 281: 67.32		RAB6A_HUMAN (1-208): 4.85e-84: 251: 89.90
+	Hs
		894712 RAB8A_HUMAN (1-199): 1.02e-96: 281: 67.32		RB11A_HUMAN (3-208): 8.53e-82: 245: 26.98
+	Sc
		350828 YPT1_YEAST (3-200): 7.2e-90: 263: 50.24		YPT1_YEAST (7-207): 3.33e-85: 254: 34.95
+	Zm
		73944 B4FAE1_MAIZE (3-200): 8.03e-89: 260: 53.23		B4FAE1_MAIZE (7-207): 1.27e-86: 257: 31.84
+	Hs
		895549 RAB10_HUMAN (1-200): 3.02e-89: 262: 100.00		RAB1B_HUMAN (7-206): 6.49e-84: 250: 32.00
+	Mm
		895587 RAB10_MOUSE (1-200): 3.02e-89: 262: 100.00		RAB1B_MOUSE (7-206): 1.35e-83: 249: 33.00
+	Hs
		895472 RAB10_HUMAN (1-200): 3.02e-89: 262: 100.00		RB11A_HUMAN (3-208): 8.53e-82: 245: 26.98
+	Mm
		919000 RAB1A_MOUSE (1-200): 4.66e-87: 256: 50.24		RAB1B_MOUSE (7-206): 1.35e-83: 249: 33.00
+	Hs
		895532 RAB10_HUMAN (1-200): 3.02e-89: 262: 100.00		RAB1C_HUMAN (7-206): 1.2e-80: 242: 31.50
+	Hs
		844666 RAB8B_HUMAN (1-198): 2.21e-100: 290: 70.20		RAB5C_HUMAN (8-178): 1.04e-44: 151: 42.11
+	Hs
		844470 RAB1A_HUMAN (1-200): 4.66e-87: 256: 50.24		RAB5C_HUMAN (8-178): 1.04e-44: 151: 42.11