HitPredict

Interactor 1: UB2D3 (P61077)
Ubiquitin-conjugating enzyme E2 D3 (EC 2.3.2.23) ((E3-independent) E2 ubiquitin-conjugating enzyme D3) (EC 2.3.2.24) (E2 ubiquitin-conjugating enzyme D3) (Ubiquitin carrier protein D3) (Ubiquitin-conjugating enzyme E2(17)KB 3) (Ubiquitin-conjugating enzyme E2-17 kDa 3) (Ubiquitin-protein ligase D3)
Gene: UBE2D3

Interactor 2: RN122 (Q9H9V4)
RING finger protein 122
Gene: RNF122

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	20553626
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	UQ_con~zf-RING_2
Common GO terms	GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process GO:0051865 - protein autoubiquitination GO:0061630 - ubiquitin protein ligase activity
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 147 Hs			1 155
+	Hs
		1204871 UB2D4_HUMAN (1-147): 8.97e-83: 241: 91.84		GOLI_HUMAN (25-154): 3.75e-31: 117: 27.66
+	Hs
		919772 UB2D2_HUMAN (1-147): 4.16e-82: 239: 97.28		GOLI_HUMAN (25-154): 3.75e-31: 117: 27.66
+	Hs
		1356934 UB2D4_HUMAN (1-147): 8.97e-83: 241: 91.84		RN150_HUMAN (28-152): 1.27e-26: 105: 23.53
+	Hs
		919789 UB2D2_HUMAN (1-147): 4.16e-82: 239: 97.28		RN149_HUMAN (34-152): 1.57e-26: 104: 27.91
+	Hs
		1148281 UB2D4_HUMAN (1-147): 8.97e-83: 241: 91.84		RNF43_HUMAN (26-148): 1.56e-24: 100: 23.36
+	Hs
		919752 UB2D2_HUMAN (1-147): 4.16e-82: 239: 97.28		RNF43_HUMAN (26-148): 1.56e-24: 100: 23.36
+	Hs
		919766 UB2D2_HUMAN (1-147): 4.16e-82: 239: 97.28		SYVN1_HUMAN (29-146): 1.2e-24: 100: 20.80
+	Hs
		1262545 UB2D4_HUMAN (1-147): 8.97e-83: 241: 91.84		ZNRF4_HUMAN (16-146): 5.4e-24: 97.8: 22.86
+	Hs
		1332598 UB2D4_HUMAN (1-147): 8.97e-83: 241: 91.84		RN167_HUMAN (24-137): 2.48e-24: 97.8: 24.79
+	Hs
		1356614 UB2D4_HUMAN (1-147): 8.97e-83: 241: 91.84		AMFR_HUMAN (32-153): 3.08e-23: 96.3: 23.31
+	Hs
		919802 UB2D2_HUMAN (1-147): 4.16e-82: 239: 97.28		ZNRF4_HUMAN (16-146): 5.4e-24: 97.8: 22.86
+	Hs
		1313520 UB2D4_HUMAN (1-147): 8.97e-83: 241: 91.84		RN126_HUMAN (89-149): 1.21e-23: 95.5: 37.71
+	Hs
		207572 UB2D4_HUMAN (1-147): 8.97e-83: 241: 91.84		RNF13_HUMAN (33-140): 8.45e-23: 94.4: 25.89
+	Hs
		919840 UB2D2_HUMAN (1-147): 4.16e-82: 239: 97.28		RN126_HUMAN (89-149): 1.21e-23: 95.5: 37.71
+	Hs
		1377467 UB2D4_HUMAN (1-147): 8.97e-83: 241: 91.84		RN115_HUMAN (83-147): 7.32e-23: 93.2: 35.39
+	Hs
		207553 UB2D2_HUMAN (1-147): 4.16e-82: 239: 97.28		RNF13_HUMAN (33-140): 8.45e-23: 94.4: 25.89
+	Zm
		74334 B4FC97_MAIZE (1-147): 8.22e-83: 241: 78.91		B6U926_MAIZE (67-145): 6.76e-22: 91.7: 26.58
+	Zm
		79637 B6SZE0_MAIZE (1-147): 1.06e-82: 241: 78.91		B6U926_MAIZE (67-145): 6.76e-22: 91.7: 26.58
+	At
		715137 UBC9_ARATH (1-147): 6.25e-82: 239: 79.59		RNG1L_ARATH (77-146): 8.33e-22: 90.9: 30.00
+	Hs
		1327690 UB2D4_HUMAN (1-147): 8.97e-83: 241: 91.84		RNF38_HUMAN (93-133): 4.57e-09: 55.8: 51.22