HitPredict

Interactor 1: UB2D3 (P61077)
Ubiquitin-conjugating enzyme E2 D3 (EC 2.3.2.23) ((E3-independent) E2 ubiquitin-conjugating enzyme D3) (EC 2.3.2.24) (E2 ubiquitin-conjugating enzyme D3) (Ubiquitin carrier protein D3) (Ubiquitin-conjugating enzyme E2(17)KB 3) (Ubiquitin-conjugating enzyme E2-17 kDa 3) (Ubiquitin-protein ligase D3)
Gene: UBE2D3

Interactor 2: RNF11 (Q9Y3C5)
RING finger protein 11
Gene: RNF11

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.83 1.00 0.915

The method score is based on:

Property Details
Experiments 19690564, 19549727, 28292929, 14562029
Identification Methods two hybrid, pull down, affinity chromatography technology, two hybrid array, enzymatic study
Interaction Type direct interaction, physical association, ubiquitination reaction

The annotation score is based on:

Property Details
Interacting Pfam domains UQ_con~zf-RING_2
Common GO terms GO:0000151 - ubiquitin ligase complex
GO:0005634 - nucleus
GO:0006511 - ubiquitin-dependent protein catabolic process
GO:0051865 - protein autoubiquitination
GO:0061630 - ubiquitin protein ligase activity
and 1 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 147
Hs

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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024