HitPredict

Interactor 1: UBE2K (P61086)
Ubiquitin-conjugating enzyme E2 K (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme K) (Huntingtin-interacting protein 2) (HIP-2) (Ubiquitin carrier protein) (Ubiquitin-conjugating enzyme E2-25 kDa) (Ubiquitin-conjugating enzyme E2(25K)) (Ubiquitin-conjugating enzyme E2-25K) (Ubiquitin-protein ligase)
Gene: UBE2K

Interactor 2: REL (Q04864)
Proto-oncogene c-Rel
Gene: REL

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.70	0.60	0.651

Property	Details
Experiments	25416956, 27107012
Identification Methods	two hybrid, two hybrid prey pooling approach, two hybrid array, validated two hybrid, barcode fusion genetics two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 200 Hs			1 619
+	Hs
		981791 UB2D4_HUMAN (4-154): 1.49e-75: 225: 41.72		REL_HUMAN (1-619): 0: 692: 100.00
+	Hs
		849310 UB2D1_HUMAN (4-154): 1.87e-75: 225: 39.74		TF65_HUMAN (2-576): 4.74e-158: 466: 37.89
+	Hs
		919709 UB2D2_HUMAN (4-154): 7.76e-75: 223: 41.06		TF65_HUMAN (2-576): 4.74e-158: 466: 37.89
+	Hs
		895779 UB2D3_HUMAN (4-154): 1.49e-73: 220: 39.74		TF65_HUMAN (2-576): 4.74e-158: 466: 37.89
+	Hs
		587507 UB2D2_HUMAN (4-154): 7.76e-75: 223: 41.06		NFKB1_HUMAN (1-375): 2e-145: 447: 37.47
+	Hs
		851805 UB2E1_HUMAN (3-153): 1.87e-66: 203: 39.74		TF65_HUMAN (2-576): 4.74e-158: 466: 37.89
+	Hs
		587492 UB2D3_HUMAN (4-154): 1.49e-73: 220: 39.74		NFKB1_HUMAN (1-375): 2e-145: 447: 37.47