HitPredict

Interactor 1: UBE2K (P61086)
Ubiquitin-conjugating enzyme E2 K (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme K) (Huntingtin-interacting protein 2) (HIP-2) (Ubiquitin carrier protein) (Ubiquitin-conjugating enzyme E2-25 kDa) (Ubiquitin-conjugating enzyme E2(25K)) (Ubiquitin-conjugating enzyme E2-25K) (Ubiquitin-protein ligase)
Gene: UBE2K

Interactor 2: BIRC8 (Q96P09)
Baculoviral IAP repeat-containing protein 8 (Inhibitor of apoptosis-like protein 2) (IAP-like protein 2) (ILP-2) (Testis-specific inhibitor of apoptosis)
Gene: BIRC8

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.621

Property	Details
Experiments	19549727
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	UQ_con~zf-C3HC4_3
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 200 Hs			1 236
+	Hs
		896319 UBE2K_HUMAN (1-200): 1.35e-82: 245: 100.00		Q6PIA0_HUMAN (1-236): 2.73e-86: 257: 99.15
+	Hs
		1298970 UB2D4_HUMAN (4-154): 1.49e-75: 225: 41.72		BIRC8_HUMAN (1-236): 1.07e-86: 258: 100.00
+	Hs
		849413 UB2D1_HUMAN (4-154): 1.87e-75: 225: 39.74		BIRC8_HUMAN (1-236): 1.07e-86: 258: 100.00
+	Hs
		896349 UBE2K_HUMAN (1-200): 1.35e-82: 245: 100.00		BIRC7_HUMAN (1-236): 4.79e-61: 195: 33.47
+	Hs
		849400 UB2D1_HUMAN (4-154): 1.87e-75: 225: 39.74		BIRC7_HUMAN (1-236): 4.79e-61: 195: 33.47
+	Hs
		849456 UB2D1_HUMAN (4-154): 1.87e-75: 225: 39.74		BIRC6_HUMAN (1-185): 2.65e-36: 137: 20.31
+	Hs
		849396 UB2D1_HUMAN (4-154): 1.87e-75: 225: 39.74		MIB2_HUMAN (37-234): 9.33e-29: 115: 19.34
+	Hs
		849387 UB2D1_HUMAN (4-154): 1.87e-75: 225: 39.74		RFFL_HUMAN (64-236): 4.82e-24: 100: 17.78
+	Hs
		1264347 UB2D4_HUMAN (4-154): 1.49e-75: 225: 41.72		MYLIP_HUMAN (166-235): 7.52e-21: 92.2: 35.71
+	Hs
		849386 UB2D1_HUMAN (4-154): 1.87e-75: 225: 39.74		MYLIP_HUMAN (166-235): 7.52e-21: 92.2: 35.71
+	Hs
		849321 UB2D1_HUMAN (4-154): 1.87e-75: 225: 39.74		BIRC3_HUMAN (4-158): 5.42e-18: 84.3: 24.20
+	Hs
		919721 UB2D2_HUMAN (4-154): 7.76e-75: 223: 41.06		BIRC3_HUMAN (4-158): 5.42e-18: 84.3: 24.20
+	Hs
		849322 UB2D1_HUMAN (4-154): 1.87e-75: 225: 39.74		BIRC2_HUMAN (4-148): 2.85e-16: 79.3: 24.49
+	Hs
		919722 UB2D2_HUMAN (4-154): 7.76e-75: 223: 41.06		BIRC2_HUMAN (4-148): 2.85e-16: 79.3: 24.49
+	Hs
		849308 UB2D1_HUMAN (4-154): 1.87e-75: 225: 39.74		XIAP_HUMAN (3-211): 1.12e-13: 71.6: 15.07
+	Hs
		957802 UB2D4_HUMAN (4-154): 1.49e-75: 225: 41.72		XIAP_HUMAN (3-211): 1.12e-13: 71.6: 15.07
+	Hs
		919707 UB2D2_HUMAN (4-154): 7.76e-75: 223: 41.06		XIAP_HUMAN (3-211): 1.12e-13: 71.6: 15.07
+	Hs
		1206094 UB2D4_HUMAN (4-154): 1.49e-75: 225: 41.72		MIB1_HUMAN (158-233): 9.18e-12: 66: 25.00
+	Hs
		849363 UB2D1_HUMAN (4-154): 1.87e-75: 225: 39.74		MIB1_HUMAN (158-233): 9.18e-12: 66: 25.00
+	Hs
		919776 UB2D2_HUMAN (4-154): 7.76e-75: 223: 41.06		MIB1_HUMAN (158-233): 9.18e-12: 66: 25.00