HitPredict

Interactor 1: UBE2N (P61088)
Ubiquitin-conjugating enzyme E2 N (EC 2.3.2.23) (Bendless-like ubiquitin-conjugating enzyme) (E2 ubiquitin-conjugating enzyme N) (Ubc13) (UbcH13) (Ubiquitin carrier protein N) (Ubiquitin-protein ligase N)
Gene: UBE2N

Interactor 2: UB2V2 (Q15819)
Ubiquitin-conjugating enzyme E2 variant 2 (DDVit 1) (Enterocyte differentiation-associated factor 1) (EDAF-1) (Enterocyte differentiation-promoting factor 1) (EDPF-1) (MMS2 homolog) (Vitamin D3-inducible protein)
Gene: UBE2V2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.98 1.00 0.991

The method score is based on:

Property Details
Experiments 16122702, 11504715, 26148049, 27173435, 32659264, 33619271, 36142504, 37071682, 15147900, 16215985, 15749714, 18678647, 12847084, 17964296, 25909880, 31638574, 33961781, 16129784, 21114314, 14517261 and 7 others

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Identification Methods affinity chromatography technology, pull down, x-ray crystallography, cross-linking study, two hybrid, anti tag coimmunoprecipitation, ubiquitinase assay, tandem affinity purification
Interaction Type physical association, direct interaction, association, ubiquitination reaction

The annotation score is based on:

Property Details
Interacting Pfam domains UQ_con~UQ_con
Common GO terms GO:0000729 - DNA double-strand break processing
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0006282 - regulation of DNA repair
and 7 others

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Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 152
Hs

1 145
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Last updated: 15 Jul 2024