HitPredict

Interactor 1: UBE2N (P61088)
Ubiquitin-conjugating enzyme E2 N (EC 2.3.2.23) (Bendless-like ubiquitin-conjugating enzyme) (E2 ubiquitin-conjugating enzyme N) (Ubc13) (UbcH13) (Ubiquitin carrier protein N) (Ubiquitin-protein ligase N)
Gene: UBE2N

Interactor 2: LRSM1 (Q6UWE0)
E3 ubiquitin-protein ligase LRSAM1 (EC 2.3.2.27) (Leucine-rich repeat and sterile alpha motif-containing protein 1) (RING-type E3 ubiquitin transferase LRSAM1) (Tsg101-associated ligase) (hTAL)
Gene: LRSAM1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.74	1.00	0.862

Property	Details
Experiments	28335037, 19690564, 19549727
Identification Methods	two hybrid, two hybrid array
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	UQ_con~zf-C3HC4_3
Common GO terms	GO:0004842 - ubiquitin-protein transferase activity GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 152 Hs			1 723
+	Hs
		1165227 UB2D4_HUMAN (4-149): 5.39e-81: 236: 45.89		LRSM1_HUMAN (1-723): 4.35e-103: 333: 100.00
+	Hs
		849345 UB2D1_HUMAN (4-149): 3.22e-80: 235: 45.21		LRSM1_HUMAN (1-723): 4.35e-103: 333: 100.00
+	Hs
		919756 UB2D2_HUMAN (4-149): 9.96e-80: 233: 46.58		LRSM1_HUMAN (1-723): 4.35e-103: 333: 100.00
+	Hs
		895817 UB2D3_HUMAN (4-149): 1.46e-78: 230: 45.89		LRSM1_HUMAN (1-723): 4.35e-103: 333: 100.00
+	Hs
		851826 UB2E1_HUMAN (1-149): 1.93e-73: 219: 45.64		LRSM1_HUMAN (1-723): 4.35e-103: 333: 100.00