HitPredict

Interactor 1: UBE2N (P61088)
Ubiquitin-conjugating enzyme E2 N (EC 2.3.2.23) (Bendless-like ubiquitin-conjugating enzyme) (E2 ubiquitin-conjugating enzyme N) (Ubc13) (UbcH13) (Ubiquitin carrier protein N) (Ubiquitin-protein ligase N)
Gene: UBE2N

Interactor 2: RNF5 (Q99942)
E3 ubiquitin-protein ligase RNF5 (EC 2.3.2.27) (RING finger protein 5) (Ram1 homolog) (HsRma1)
Gene: RNF5

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	19269966
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	UQ_con~zf-C3HC4_3
Common GO terms	GO:0004842 - ubiquitin-protein transferase activity GO:0070534 - protein K63-linked ubiquitination
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 152 Hs			1 180
+	Hs
		1307272 UB2D4_HUMAN (4-149): 5.39e-81: 236: 45.89		RNF5_HUMAN (1-164): 8.79e-56: 175: 100.00
+	Hs
		849424 UB2D1_HUMAN (4-149): 3.22e-80: 235: 45.21		RNF5_HUMAN (1-164): 8.79e-56: 175: 100.00
+	Hs
		1292368 UB2D4_HUMAN (4-149): 5.39e-81: 236: 45.89		RN185_HUMAN (17-179): 7.02e-52: 166: 60.98
+	Hs
		849409 UB2D1_HUMAN (4-149): 3.22e-80: 235: 45.21		RN185_HUMAN (17-179): 7.02e-52: 166: 60.98
+	At
		715141 UBC9_ARATH (4-149): 7.83e-80: 234: 46.58		Q9LN67_ARATH (6-168): 4.25e-35: 124: 26.94
+	Hs
		849406 UB2D1_HUMAN (4-149): 3.22e-80: 235: 45.21		TRI11_HUMAN (14-148): 2.69e-31: 119: 17.78
+	Hs
		849314 UB2D1_HUMAN (4-149): 3.22e-80: 235: 45.21		TRI26_HUMAN (14-123): 1.73e-28: 112: 21.85
+	Hs
		1318532 UB2D4_HUMAN (4-149): 5.39e-81: 236: 45.89		TRI31_HUMAN (19-126): 9.14e-27: 106: 20.91
+	Hs
		849437 UB2D1_HUMAN (4-149): 3.22e-80: 235: 45.21		TRI31_HUMAN (19-126): 9.14e-27: 106: 20.91
+	Hs
		1336390 UB2D4_HUMAN (4-149): 5.39e-81: 236: 45.89		TRI39_HUMAN (24-148): 5.72e-26: 104: 21.43
+	Hs
		849453 UB2D1_HUMAN (4-149): 3.22e-80: 235: 45.21		TRI39_HUMAN (24-148): 5.72e-26: 104: 21.43
+	Hs
		584907 UB2D1_HUMAN (4-149): 3.22e-80: 235: 45.21		RO52_HUMAN (23-148): 9.12e-25: 101: 18.11
+	Hs
		1354526 UB2D4_HUMAN (4-149): 5.39e-81: 236: 45.89		TRI10_HUMAN (14-156): 5.89e-24: 99: 17.45
+	Hs
		849366 UB2D1_HUMAN (4-149): 3.22e-80: 235: 45.21		TRI22_HUMAN (20-126): 2e-24: 100: 19.64
+	Hs
		849475 UB2D1_HUMAN (4-149): 3.22e-80: 235: 45.21		TRI10_HUMAN (14-156): 5.89e-24: 99: 17.45
+	Hs
		262201 UB2D4_HUMAN (4-149): 5.39e-81: 236: 45.89		TRIM3_HUMAN (3-109): 3.92e-21: 91.3: 19.84
+	Hs
		262161 UB2D1_HUMAN (4-149): 3.22e-80: 235: 45.21		TRIM3_HUMAN (3-109): 3.92e-21: 91.3: 19.84
+	Hs
		849438 UB2D1_HUMAN (4-149): 3.22e-80: 235: 45.21		TRIM7_HUMAN (1-101): 4.17e-21: 91.3: 23.48
+	Hs
		849487 UB2D1_HUMAN (4-149): 3.22e-80: 235: 45.21		CBLC_HUMAN (6-93): 1.05e-19: 87.1: 28.28
+	Hs
		749252 UB2D1_HUMAN (4-149): 3.22e-80: 235: 45.21		BRCA1_HUMAN (25-76): 3.12e-19: 86.4: 34.62