HitPredict

Interactor 1: UBE2N (P61088)
Ubiquitin-conjugating enzyme E2 N (EC 2.3.2.23) (Bendless-like ubiquitin-conjugating enzyme) (E2 ubiquitin-conjugating enzyme N) (Ubc13) (UbcH13) (Ubiquitin carrier protein N) (Ubiquitin-protein ligase N)
Gene: UBE2N

Interactor 2: TRI54 (Q9BYV2)
Tripartite motif-containing protein 54 (Muscle-specific RING finger protein) (MuRF) (Muscle-specific RING finger protein 3) (MuRF-3) (MuRF3) (RING finger protein 30)
Gene: TRIM54

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	23695783
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	UQ_con~zf-RING_UBOX
Common GO terms	GO:0005737 - cytoplasm GO:0016567 - protein ubiquitination
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 152 Hs			1 358
+	Hs
		1356055 UB2D4_HUMAN (4-149): 5.39e-81: 236: 45.89		TRIM1_HUMAN (17-333): 6.09e-86: 276: 22.62
+	Hs
		1151762 UB2D4_HUMAN (4-149): 5.39e-81: 236: 45.89		Q6GX22_HUMAN (17-333): 2.1e-85: 273: 22.62
+	Hs
		1317493 UB2D4_HUMAN (4-149): 5.39e-81: 236: 45.89		TRI54_HUMAN (1-358): 7.84e-87: 267: 100.00
+	Hs
		584907 UB2D1_HUMAN (4-149): 3.22e-80: 235: 45.21		RO52_HUMAN (11-358): 3.3e-75: 241: 17.14
+	Hs
		1336390 UB2D4_HUMAN (4-149): 5.39e-81: 236: 45.89		TRI39_HUMAN (17-358): 1.52e-70: 230: 17.87
+	Hs
		1318738 UB2D4_HUMAN (4-149): 5.39e-81: 236: 45.89		TRIM2_HUMAN (14-353): 9.22e-68: 228: 19.03
+	Hs
		537142 UB2D4_HUMAN (4-149): 5.39e-81: 236: 45.89		TRI27_HUMAN (11-358): 2.55e-69: 227: 17.30
+	Hs
		536760 UB2D1_HUMAN (4-149): 3.22e-80: 235: 45.21		TRI27_HUMAN (11-358): 2.55e-69: 227: 17.30
+	Hs
		262201 UB2D4_HUMAN (4-149): 5.39e-81: 236: 45.89		TRIM3_HUMAN (14-353): 4.27e-64: 218: 19.71
+	Hs
		262161 UB2D1_HUMAN (4-149): 3.22e-80: 235: 45.21		TRIM3_HUMAN (14-353): 4.27e-64: 218: 19.71
+	Hs
		1318719 UB2D4_HUMAN (4-149): 5.39e-81: 236: 45.89		TRIM5_HUMAN (12-354): 6.76e-65: 215: 15.95
+	Hs
		135045 UB2D4_HUMAN (4-149): 5.39e-81: 236: 45.89		TRI38_HUMAN (11-357): 9.66e-64: 211: 18.05
+	Hs
		1285831 UB2D4_HUMAN (4-149): 5.39e-81: 236: 45.89		TRI43_HUMAN (12-320): 1.99e-63: 210: 16.77
+	Hs
		135012 UB2D1_HUMAN (4-149): 3.22e-80: 235: 45.21		TRI38_HUMAN (11-357): 9.66e-64: 211: 18.05
+	Hs
		1354526 UB2D4_HUMAN (4-149): 5.39e-81: 236: 45.89		TRI10_HUMAN (11-358): 1.94e-62: 208: 16.34
+	Hs
		1377469 UB2D4_HUMAN (4-149): 5.39e-81: 236: 45.89		TRI17_HUMAN (11-354): 4.46e-62: 207: 19.19
+	Hs
		175730 UB2D4_HUMAN (4-149): 5.39e-81: 236: 45.89		TRI18_HUMAN (46-333): 8.71e-60: 205: 22.49
+	Hs
		175653 UB2D1_HUMAN (4-149): 3.22e-80: 235: 45.21		TRI18_HUMAN (46-333): 8.71e-60: 205: 22.49
+	Hs
		1318532 UB2D4_HUMAN (4-149): 5.39e-81: 236: 45.89		TRI31_HUMAN (11-303): 1.56e-60: 202: 22.53
+	Hs
		1204911 UB2D4_HUMAN (4-149): 5.39e-81: 236: 45.89		TRI50_HUMAN (16-270): 9.01e-13: 70.9: 25.10