HitPredict

Interactor 1: ARP3 (P61158)
Actin-related protein 3 (Actin-like protein 3)
Gene: ACTR3

Interactor 2: DYST (Q03001)
Dystonin (230 kDa bullous pemphigoid antigen) (230/240 kDa bullous pemphigoid antigen) (Bullous pemphigoid antigen 1) (BPA) (Bullous pemphigoid antigen) (Dystonia musculorum protein) (Hemidesmosomal plaque protein)
Gene: DST

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Actin~CH
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005925 - focal adhesion GO:0015629 - actin cytoskeleton and 1 others more... GO:0016020 - membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 418 Hs			1 7570
+	Hs
		891706 ACTB_HUMAN (1-414): 0: 539: 35.66		DYST_HUMAN (1-7570): 0: 2600: 100.00
+	Hs
		932113 ACTC_HUMAN (3-414): 0: 527: 35.59		DYST_HUMAN (1-7570): 0: 2600: 100.00
+	Hs
		521515 ARP3_HUMAN (1-418): 0: 588: 100.00		ACTN1_HUMAN (3770-4283): 1.06e-26: 123: 10.00
+	Hs
		513848 ACTS_HUMAN (3-414): 0: 528: 35.59		DMD_HUMAN (383-1643): 8.98e-27: 124: 11.75
+	Hs
		891697 ACTB_HUMAN (1-414): 0: 539: 35.66		SPTB2_HUMAN (5709-7570): 7.99e-22: 108: 12.95
+	Hs
		929824 ACTG_HUMAN (1-414): 0: 538: 35.42		SPTB2_HUMAN (5709-7570): 7.99e-22: 108: 12.95
+	Hs
		892113 ACTB_HUMAN (1-414): 0: 539: 35.66		MACF1_HUMAN (351-1936): 4.95e-21: 105: 11.05
+	Hs
		932107 ACTC_HUMAN (3-414): 0: 527: 35.59		SPTB2_HUMAN (5709-7570): 7.99e-22: 108: 12.95
+	Hs
		164588 ACTB_HUMAN (1-414): 0: 539: 35.66		SPTN2_HUMAN (5708-7163): 4.91e-17: 92.5: 14.91
+	Hs
		891755 ACTB_HUMAN (1-414): 0: 539: 35.66		SPTN1_HUMAN (269-874): 2.44e-13: 80.3: 13.42
+	Hs
		929856 ACTG_HUMAN (1-414): 0: 538: 35.42		SPTN1_HUMAN (269-874): 2.44e-13: 80.3: 13.42
+	Hs
		929869 ACTG_HUMAN (1-414): 0: 538: 35.42		PLEC_HUMAN (1777-1974): 1.7e-12: 77.5: 19.19
+	Hs
		809100 ACTC_HUMAN (3-414): 0: 527: 35.59		UTRN_HUMAN (264-1530): 1.26e-14: 84.8: 9.65
+	Hs
		932975 ACTS_HUMAN (3-414): 0: 528: 35.59		SPTN1_HUMAN (269-874): 2.44e-13: 80.3: 13.42
+	Hs
		932145 ACTC_HUMAN (3-414): 0: 527: 35.59		SPTN1_HUMAN (269-874): 2.44e-13: 80.3: 13.42
+	Hs
		506816 ACTB_HUMAN (1-414): 0: 539: 35.66		SPTB1_HUMAN (3189-4877): 1.07e-09: 68.2: 8.03
+	Hs
		932288 ACTC_HUMAN (3-414): 0: 527: 35.59		SYNE2_HUMAN (282-1774): 1.65e-12: 77.9: 8.82
+	Hs
		932171 ACTC_HUMAN (3-414): 0: 527: 35.59		PLEC_HUMAN (1777-1974): 1.7e-12: 77.5: 19.19
+	Dm
		284844 ACT1_DROME (3-414): 0: 534: 35.35		O77291_DROME (5467-6003): 8.81e-09: 65.1: 20.07
+	Hs
		932157 ACTC_HUMAN (3-414): 0: 527: 35.59		GOGB1_HUMAN (1119-1866): 1.3e-10: 71.3: 6.59