HitPredict

Interactor 1: ARP3 (P61158)
Actin-related protein 3 (Actin-like protein 3)
Gene: ACTR3

Interactor 2: WASF1 (Q92558)
Actin-binding protein WASF1 (Protein WAVE-1) (Verprolin homology domain-containing protein 1) (Wiskott-Aldrich syndrome protein family member 1) (WASP family protein member 1)
Gene: WASF1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.58	1.00	0.768

Property	Details
Experiments	12829704, 34079125
Identification Methods	pull down, proximity labelling technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	Actin~WH2
Common GO terms	GO:0005829 - cytosol GO:0005925 - focal adhesion GO:0015629 - actin cytoskeleton GO:0030027 - lamellipodium
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 418 Hs			1 559
+	Hs
		929950 ACTG_HUMAN (1-414): 0: 538: 35.42		WASF1_HUMAN (1-559): 2.63e-73: 245: 100.00
+	Rn
		892225 ACTB_RAT (1-414): 0: 539: 35.66		WASF1_RAT (1-559): 1.61e-69: 235: 97.50
+	Hs
		896852 ARP3_HUMAN (1-418): 0: 588: 100.00		WASF3_HUMAN (1-557): 1.12e-43: 164: 45.73
+	Hs
		896858 ARP3_HUMAN (1-418): 0: 588: 100.00		WASF2_HUMAN (1-541): 2.37e-42: 160: 42.14
+	At
		1338960 ARP3_ARATH (6-417): 0: 523: 59.10		SCAR3_ARATH (1-163): 1.01e-51: 192: 22.16
+	Hs
		930055 ACTG_HUMAN (1-414): 0: 538: 35.42		WASF3_HUMAN (1-557): 1.12e-43: 164: 45.73
+	Hs
		892150 ACTB_HUMAN (1-414): 0: 539: 35.66		WASF2_HUMAN (1-541): 2.37e-42: 160: 42.14
+	Hs
		930077 ACTG_HUMAN (1-414): 0: 538: 35.42		WASF2_HUMAN (1-541): 2.37e-42: 160: 42.14
+	Hs
		932482 ACTC_HUMAN (3-414): 0: 527: 35.59		WASF2_HUMAN (1-541): 2.37e-42: 160: 42.14
+	Hs
		891726 ACTB_HUMAN (1-414): 0: 539: 35.66		EP300_HUMAN (77-554): 1.1e-28: 124: 14.91
+	Hs
		932966 ACTS_HUMAN (3-414): 0: 528: 35.59		EP300_HUMAN (77-554): 1.1e-28: 124: 14.91
+	Hs
		915369 ACTA_HUMAN (3-414): 0: 526: 35.59		EP300_HUMAN (77-554): 1.1e-28: 124: 14.91
+	Hs
		554290 ACTA_HUMAN (3-414): 0: 526: 35.59		MUC1_HUMAN (188-550): 1.54e-14: 79: 12.95
+	Hs
		203220 ACTC_HUMAN (3-414): 0: 527: 35.59		SYNJ1_HUMAN (41-523): 2.02e-11: 69: 12.53