HitPredict

Interactor 1: ARP2 (P61160)
Actin-related protein 2 (Actin-like protein 2)
Gene: ACTR2

Interactor 2: LUZP1 (Q86V48)
Leucine zipper protein 1
Gene: LUZP1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	26496610
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0016020 - membrane GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 394 Hs			1 1076
+	Hs
		891872 ACTB_HUMAN (1-388): 0: 574: 46.65		LUZP1_HUMAN (1-1076): 0: 616: 100.00
+	Hs
		896944 ARP2_HUMAN (1-394): 0: 815: 100.00		MY18A_HUMAN (4-516): 2.88e-29: 129: 11.91
+	Hs
		148602 ARP2_HUMAN (1-394): 0: 815: 100.00		CTRO_HUMAN (2-458): 4.05e-25: 115: 14.56
+	Hs
		896980 ARP2_HUMAN (1-394): 0: 815: 100.00		MYO5C_HUMAN (9-401): 4.77e-16: 86: 16.50
+	Hs
		724743 ARP2_HUMAN (1-394): 0: 815: 100.00		MYH9_HUMAN (385-763): 9.36e-12: 71.6: 8.83
+	Hs
		891935 ACTB_HUMAN (1-388): 0: 574: 46.65		MY18A_HUMAN (4-516): 2.88e-29: 129: 11.91
+	Hs
		929952 ACTG_HUMAN (3-388): 0: 573: 46.37		MY18A_HUMAN (4-516): 2.88e-29: 129: 11.91
+	Dm
		116373 ACT1_DROME (1-388): 0: 575: 45.88		M9PI41_DROME (1-563): 2.66e-22: 106: 9.57
+	Dm
		116372 ACT2_DROME (1-388): 0: 574: 45.62		M9PI41_DROME (1-563): 2.66e-22: 106: 9.57
+	Rn
		892236 ACTB_RAT (1-388): 0: 574: 46.65		MYH10_RAT (245-788): 8.44e-20: 98.2: 8.45
+	Hs
		725135 ACTH_HUMAN (1-388): 0: 569: 45.62		MYH10_HUMAN (2-451): 8.79e-21: 101: 14.79
+	Mm
		892205 ACTB_MOUSE (1-388): 0: 574: 46.65		MYH9_MOUSE (234-788): 1.37e-17: 90.9: 9.48
+	Hs
		930015 ACTG_HUMAN (3-388): 0: 573: 46.37		MYO5C_HUMAN (9-401): 4.77e-16: 86: 16.50
+	Rn
		892228 ACTB_RAT (1-388): 0: 574: 46.65		MYH9_RAT (351-837): 1.93e-12: 74: 9.51
+	Hs
		724738 ACTB_HUMAN (1-388): 0: 574: 46.65		MYH9_HUMAN (385-763): 9.36e-12: 71.6: 8.83
+	Hs
		724762 ACTG_HUMAN (3-388): 0: 573: 46.37		MYH9_HUMAN (385-763): 9.36e-12: 71.6: 8.83
+	Hs
		929869 ACTG_HUMAN (3-388): 0: 573: 46.37		PLEC_HUMAN (35-503): 1.33e-11: 71.4: 16.50
+	Rn
		92841 ACTB_RAT (1-388): 0: 574: 46.65		CTRO_RAT (363-780): 2.9e-11: 70.1: 9.32
+	Hs
		724767 ACTS_HUMAN (2-388): 0: 569: 46.51		MYH9_HUMAN (385-763): 9.36e-12: 71.6: 8.83
+	Mm
		930101 ACTH_MOUSE (1-388): 0: 569: 45.62		PLEC_MOUSE (3-390): 6.63e-09: 62.5: 19.86