HitPredict

Interactor 1: ARP2 (P61160)
Actin-related protein 2 (Actin-like protein 2)
Gene: ACTR2

Interactor 2: MYO10 (Q9HD67)
Unconventional myosin-X (Unconventional myosin-10)
Gene: MYO10

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	36861887
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Actin~Myosin_head
Common GO terms	GO:0005524 - ATP binding GO:0005829 - cytosol GO:0051015 - actin filament binding
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 394 Hs			1 2058
+	Hs
		892049 ACTB_HUMAN (1-388): 0: 574: 46.65		MYO10_HUMAN (1-2058): 0: 1985: 100.00
+	Hs
		930011 ACTG_HUMAN (3-388): 0: 573: 46.37		MYO10_HUMAN (1-2058): 0: 1985: 100.00
+	Hs
		896980 ARP2_HUMAN (1-394): 0: 815: 100.00		MYO5C_HUMAN (3-1311): 0: 939: 25.88
+	Hs
		930015 ACTG_HUMAN (3-388): 0: 573: 46.37		MYO5C_HUMAN (3-1311): 0: 939: 25.88
+	Hs
		932396 ACTC_HUMAN (2-388): 0: 569: 46.51		MYO5C_HUMAN (3-1311): 0: 939: 25.88
+	Sc
		691273 ACT_YEAST (1-387): 0: 565: 45.74		MYO4_YEAST (3-1023): 0: 921: 29.55
+	Sp
		293470 ACT_SCHPO (3-388): 0: 565: 45.60		MYO52_SCHPO (5-924): 4.6e-151: 510: 34.11
+	Rn
		892236 ACTB_RAT (1-388): 0: 574: 46.65		MYH10_RAT (693-1105): 6.49e-17: 90.2: 12.61
+	Hs
		725135 ACTH_HUMAN (1-388): 0: 569: 45.62		MYH10_HUMAN (693-1105): 3.34e-17: 90.9: 12.83
+	Hs
		725136 ACTC_HUMAN (2-388): 0: 569: 46.51		MYH10_HUMAN (693-1105): 3.34e-17: 90.9: 12.83
+	Sc
		585356 ACT_YEAST (1-387): 0: 565: 45.74		MYO2_YEAST (957-1178): 3.86e-11: 70.9: 7.36