HitPredict

Interactor 1: DRD2 (P61168)
D(2) dopamine receptor (Dopamine D2 receptor)
Gene: DRD2

Interactor 2: SH3G2 (Q62420)
Endophilin-A1 (Endophilin-1) (SH3 domain protein 2A) (SH3 domain-containing GRB2-like protein 2) (SH3p4)
Gene: Sh3gl2

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	20551902
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0030672 - synaptic vesicle membrane GO:0098978 - glutamatergic synapse
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 444 Mm			1 352
+	Hs
		445810 ADA2A_HUMAN (2-443): 1e-79: 256: 29.93		SH3G2_HUMAN (1-352): 3.65e-93: 283: 98.86
+	Hs
		574792 ADA2B_HUMAN (43-443): 5.78e-79: 253: 29.79		SH3G2_HUMAN (1-352): 3.65e-93: 283: 98.86
+	Hs
		445811 ADA2A_HUMAN (2-443): 1e-79: 256: 29.93		SH3G3_HUMAN (1-352): 7.71e-91: 277: 65.34
+	Hs
		436948 ACM4_HUMAN (3-444): 1.58e-76: 248: 23.99		SH3G2_HUMAN (1-352): 3.65e-93: 283: 98.86
+	Hs
		436949 ACM4_HUMAN (3-444): 1.58e-76: 248: 23.99		SH3G3_HUMAN (1-352): 7.71e-91: 277: 65.34
+	Hs
		723748 DRD3_HUMAN (8-444): 2.35e-73: 237: 47.06		SH3G2_HUMAN (1-352): 3.65e-93: 283: 98.86
+	Hs
		445809 ADA2A_HUMAN (2-443): 1e-79: 256: 29.93		SH3G1_HUMAN (1-352): 4.31e-85: 263: 69.29
+	Hs
		574791 ADA2B_HUMAN (43-443): 5.78e-79: 253: 29.79		SH3G1_HUMAN (1-352): 4.31e-85: 263: 69.29
+	Hs
		723002 HRH1_HUMAN (1-443): 1.29e-70: 233: 22.72		SH3G2_HUMAN (1-352): 3.65e-93: 283: 98.86
+	Hs
		723749 DRD3_HUMAN (8-444): 2.35e-73: 237: 47.06		SH3G3_HUMAN (1-352): 7.71e-91: 277: 65.34
+	Hs
		436885 ACM2_HUMAN (23-444): 1.02e-69: 229: 23.39		SH3G2_HUMAN (1-352): 3.65e-93: 283: 98.86
+	Hs
		436947 ACM4_HUMAN (3-444): 1.58e-76: 248: 23.99		SH3G1_HUMAN (1-352): 4.31e-85: 263: 69.29
+	Hs
		723003 HRH1_HUMAN (1-443): 1.29e-70: 233: 22.72		SH3G3_HUMAN (1-352): 7.71e-91: 277: 65.34
+	Hs
		723747 DRD3_HUMAN (8-444): 2.35e-73: 237: 47.06		SH3G1_HUMAN (1-352): 4.31e-85: 263: 69.29
+	Hs
		723001 HRH1_HUMAN (1-443): 1.29e-70: 233: 22.72		SH3G1_HUMAN (1-352): 4.31e-85: 263: 69.29
+	Hs
		436884 ACM2_HUMAN (23-444): 1.02e-69: 229: 23.39		SH3G1_HUMAN (1-352): 4.31e-85: 263: 69.29
+	Hs
		1307428 HRH3_HUMAN (48-443): 4.79e-59: 201: 20.69		SH3G1_HUMAN (1-352): 4.31e-85: 263: 69.29
+	Hs
		723735 DRD3_HUMAN (8-444): 2.35e-73: 237: 47.06		GRB2_HUMAN (295-351): 1.18e-12: 68.2: 43.10
+	Hs
		686252 GASR_HUMAN (10-441): 1.22e-62: 211: 16.51		GRB2_HUMAN (295-351): 1.18e-12: 68.2: 43.10
+	Hs
		602194 DRD4_HUMAN (42-444): 6.18e-61: 205: 35.37		GRB2_HUMAN (295-351): 1.18e-12: 68.2: 43.10