HitPredict

Interactor 1: CSN2 (P61201)
COP9 signalosome complex subunit 2 (SGN2) (Signalosome subunit 2) (Alien homolog) (JAB1-containing signalosome subunit 2) (Thyroid receptor-interacting protein 15) (TR-interacting protein 15) (TRIP-15)
Gene: COPS2

Interactor 2: NHRF2 (Q15599)
Na(+)/H(+) exchange regulatory cofactor NHE-RF2 (NHERF-2) (NHE3 kinase A regulatory protein E3KARP) (SRY-interacting protein 1) (SIP-1) (Sodium-hydrogen exchanger regulatory factor 2) (Solute carrier family 9 isoform A3 regulatory factor 2) (Tyrosine kinase activator protein 1) (TKA-1)
Gene: NHERF2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 443 Hs			1 337
+	Hs
		1075446 CSN4_HUMAN (54-440): 8.14e-74: 238: 16.25		NHRF2_HUMAN (1-337): 6.02e-79: 246: 100.00
+	Hs
		1024162 CSN1_HUMAN (17-443): 7.03e-80: 257: 15.02		SCRIB_HUMAN (4-185): 3.63e-13: 72.7: 18.37
+	Hs
		1024249 CSN1_HUMAN (17-443): 7.03e-80: 257: 15.02		USH1C_HUMAN (142-310): 4.02e-13: 71.9: 14.54