HitPredict

Interactor 1: RAP1B (P61224)
Ras-related protein Rap-1b (EC 3.6.5.2) (GTP-binding protein smg p21B)
Gene: RAP1B

Interactor 2: STAM1 (Q92783)
Signal transducing adapter molecule 1 (STAM-1)
Gene: STAM

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 184 Hs			1 540
+	Hs
		349542 RASH_HUMAN (1-167): 1.22e-55: 175: 57.49		STAM1_HUMAN (1-518): 1.32e-126: 382: 100.00
+	Hs
		276983 RASH_HUMAN (1-167): 1.22e-55: 175: 57.49		STAM2_HUMAN (1-533): 8.53e-122: 369: 54.65
+	Hs
		241161 RAC1_HUMAN (1-184): 1.05e-68: 209: 27.55		TOM1_HUMAN (6-454): 3.66e-69: 232: 16.81
+	Hs
		914412 RB11A_HUMAN (4-178): 2.05e-69: 211: 28.98		GGA3_HUMAN (1-530): 3.3e-63: 221: 15.64
+	Hs
		913994 RB11A_HUMAN (4-178): 2.05e-69: 211: 28.98		GRB2_HUMAN (215-265): 2.32e-13: 71.2: 54.90
+	Hs
		924749 RAB1C_HUMAN (4-179): 1.37e-69: 211: 30.51		GRB2_HUMAN (215-265): 2.32e-13: 71.2: 54.90
+	Hs
		924448 RAC1_HUMAN (1-184): 1.05e-68: 209: 27.55		GRB2_HUMAN (215-265): 2.32e-13: 71.2: 54.90
+	Hs
		924763 RIT1_HUMAN (2-180): 7.98e-57: 179: 49.16		GRB2_HUMAN (215-265): 2.32e-13: 71.2: 54.90
+	Hs
		349233 RASH_HUMAN (1-167): 1.22e-55: 175: 57.49		GRB2_HUMAN (215-265): 2.32e-13: 71.2: 54.90
+	Hs
		350048 RASK_HUMAN (1-167): 6.26e-55: 174: 57.49		GRB2_HUMAN (215-265): 2.32e-13: 71.2: 54.90
+	Hs
		924814 RIT2_HUMAN (2-178): 1.4e-54: 174: 46.89		GRB2_HUMAN (215-265): 2.32e-13: 71.2: 54.90
+	Hs
		348603 RASN_HUMAN (1-167): 5.03e-54: 171: 56.89		GRB2_HUMAN (215-265): 2.32e-13: 71.2: 54.90