HitPredict

Interactor 1: STX1B (P61266)
Syntaxin-1B (Syntaxin-1B1) (Syntaxin-1B2)
Gene: STX1B

Interactor 2: SNAB (Q9H115)
Beta-soluble NSF attachment protein (SNAP-beta) (N-ethylmaleimide-sensitive factor attachment protein beta)
Gene: NAPB

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.61	1.00	0.783

Property	Details
Experiments	32296183, unassigned1304
Identification Methods	two hybrid, two hybrid prey pooling approach, two hybrid array, validated two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	SNAP~SNARE, SNAP~Syntaxin
Common GO terms	GO:0006886 - intracellular protein transport GO:0010807 - regulation of synaptic vesicle priming
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 288 Hs			1 298
+	Hs
		699286 STX2_HUMAN (1-287): 3.89e-80: 245: 64.81		SNAB_HUMAN (1-298): 3.42e-116: 338: 100.00
+	Hs
		1083986 STX1A_HUMAN (1-286): 1.75e-76: 236: 81.88		SNAB_HUMAN (1-298): 3.42e-116: 338: 100.00
+	Mm
		192858 STX1A_MOUSE (1-287): 1.14e-78: 241: 82.29		SNAA_MOUSE (1-293): 4.83e-109: 319: 83.62
+	Rn
		699171 STX1A_RAT (1-287): 1.6e-78: 241: 81.94		SNAA_RAT (1-293): 2.2e-108: 318: 82.94
+	Hs
		873547 STX1A_HUMAN (1-286): 1.75e-76: 236: 81.88		SNAA_HUMAN (1-293): 7.24e-109: 319: 83.96
+	Hs
		1017786 STX4_HUMAN (1-286): 5e-61: 197: 46.28		SNAB_HUMAN (1-298): 3.42e-116: 338: 100.00
+	Dm
		1095554 STX1A_DROME (2-282): 4.03e-72: 225: 69.01		SNAP_DROME (5-292): 1.02e-103: 306: 62.15
+	Hs
		1030185 STX3_HUMAN (1-288): 7.86e-59: 191: 59.79		SNAB_HUMAN (1-298): 3.42e-116: 338: 100.00
+	Hs
		1328433 X5D7S1_HUMAN (1-285): 2.4e-59: 191: 68.53		SNAB_HUMAN (1-298): 3.42e-116: 338: 100.00
+	Hs
		873535 STX4_HUMAN (1-286): 5e-61: 197: 46.28		SNAA_HUMAN (1-293): 7.24e-109: 319: 83.96
+	Hs
		873540 STX3_HUMAN (1-288): 7.86e-59: 191: 59.79		SNAA_HUMAN (1-293): 7.24e-109: 319: 83.96
+	Hs
		152174 STX16_HUMAN (27-263): 2.56e-50: 170: 21.99		SNAB_HUMAN (1-298): 3.42e-116: 338: 100.00
+	Hs
		178768 STX7_HUMAN (34-284): 2.16e-49: 165: 21.65		SNAB_HUMAN (1-298): 3.42e-116: 338: 100.00
+	Hs
		269400 STX11_HUMAN (1-273): 3.99e-53: 176: 33.57		SNAA_HUMAN (1-293): 7.24e-109: 319: 83.96
+	Hs
		152142 STX16_HUMAN (27-263): 2.56e-50: 170: 21.99		SNAA_HUMAN (1-293): 7.24e-109: 319: 83.96
+	Hs
		178454 STX7_HUMAN (34-284): 2.16e-49: 165: 21.65		SNAA_HUMAN (1-293): 7.24e-109: 319: 83.96
+	Dm
		1098094 STX1A_DROME (2-282): 4.03e-72: 225: 69.01		Q9U6R9_DROME (4-265): 3.27e-59: 193: 19.70
+	Dm
		1098102 STX1A_DROME (2-282): 4.03e-72: 225: 69.01		Q9VH25_DROME (42-265): 8.61e-52: 173: 19.03
+	Hs
		152173 STX16_HUMAN (27-263): 2.56e-50: 170: 21.99		SNAG_HUMAN (4-251): 6.3e-69: 218: 24.30
+	Hs
		178743 STX7_HUMAN (34-284): 2.16e-49: 165: 21.65		SNAG_HUMAN (4-251): 6.3e-69: 218: 24.30