HitPredict

Interactor 1: D6R9G5 (D6R9G5)
Kelch like family member 2
Gene: KLHL2

Interactor 2: TRIM8 (Q9BZR9)
E3 ubiquitin-protein ligase TRIM8 (EC 2.3.2.27) (Glioblastoma-expressed RING finger protein) (RING finger protein 27) (RING-type E3 ubiquitin transferase TRIM8) (Tripartite motif-containing protein 8)
Gene: TRIM8

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.50	0.407

Property	Details
Experiments	28514442
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 144 Hs			1 551
+	Hs
		307212 KLHL2_HUMAN (1-144): 7.79e-44: 153: 70.83		TRIM8_HUMAN (1-551): 4.58e-135: 405: 100.00
+	Hs
		89984 D6R9G5_HUMAN (1-144): 1.71e-57: 177: 100.00		TRIM9_HUMAN (45-397): 2.93e-56: 202: 16.30
+	Hs
		89978 D6R9G5_HUMAN (1-144): 1.71e-57: 177: 100.00		TRI47_HUMAN (13-298): 2.05e-50: 185: 21.28
+	Hs
		307213 KLHL2_HUMAN (1-144): 7.79e-44: 153: 70.83		TRIM9_HUMAN (45-397): 2.93e-56: 202: 16.30
+	Hs
		1235454 LZTR1_HUMAN (25-142): 1.22e-23: 97.1: 22.95		TRIM5_HUMAN (1-521): 1.5e-74: 246: 14.08
+	Hs
		307204 KLHL2_HUMAN (1-144): 7.79e-44: 153: 70.83		TRI47_HUMAN (13-298): 2.05e-50: 185: 21.28
+	Hs
		1357688 KLH20_HUMAN (39-143): 3.74e-27: 107: 30.70		TRI33_HUMAN (14-534): 5.05e-61: 220: 14.95
+	Hs
		1299554 KLHL5_HUMAN (62-143): 1.86e-24: 99.5: 29.55		TRIM2_HUMAN (10-495): 3.74e-61: 216: 14.23
+	Hs
		1049207 KEAP1_HUMAN (42-143): 1.51e-23: 96.8: 21.74		TRI25_HUMAN (8-365): 1.14e-59: 210: 22.31
+	Hs
		1233687 KLH36_HUMAN (58-143): 4.62e-25: 101: 29.89		TRI63_HUMAN (2-347): 1.63e-59: 202: 19.67
+	Hs
		1103540 KLH38_HUMAN (65-143): 1.95e-24: 99.4: 35.00		TRI54_HUMAN (2-347): 4.95e-59: 202: 17.76
+	Hs
		1103512 KLH38_HUMAN (65-143): 1.95e-24: 99.4: 35.00		TRI42_HUMAN (7-504): 6.66e-56: 201: 15.71
+	Hs
		1233690 KLH36_HUMAN (58-143): 4.62e-25: 101: 29.89		TRI55_HUMAN (2-347): 8.15e-53: 190: 19.18
+	Hs
		307193 KLHL2_HUMAN (1-144): 7.79e-44: 153: 70.83		TRI50_HUMAN (9-252): 3.32e-13: 73.9: 23.36