Interactor 1: PHS (P61458)
Pterin-4-alpha-carbinolamine dehydratase (PHS) (EC 4.2.1.96) (4-alpha-hydroxy-tetrahydropterin dehydratase) (Dimerization cofactor of hepatocyte nuclear factor 1-alpha) (DCoH) (Dimerization cofactor of HNF1) (Phenylalanine hydroxylase-stimulating protein) (Pterin carbinolamine dehydratase) (PCD)
Gene: Pcbd1

Interactor 2: PHS2 (Q9CZL5)
Pterin-4-alpha-carbinolamine dehydratase 2 (PHS 2) (EC 4.2.1.96) (4-alpha-hydroxy-tetrahydropterin dehydratase 2) (DcoH-like protein DCoHm) (Dimerization cofactor of hepatocyte nuclear factor 1 from muscle) (HNF-1-alpha dimerization cofactor)
Gene: Pcbd2

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 15182178
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Pterin_4a~Pterin_4a
Common GO terms GO:0004505 - phenylalanine 4-monooxygenase activity
GO:0005634 - nucleus
GO:0006729 - tetrahydrobiopterin biosynthetic process
GO:0008124 - 4-alpha-hydroxytetrahydrobiopterin dehydratase activity
GO:0045893 - positive regulation of DNA-templated transcription
Homologous interactions 5

Homologous interactions

Color coding for hit scores

1 104
Mm

1 136
+ Hs
+ Mm
+ Hs
+ Sp
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024